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Literature summary extracted from

  • Melton, E.M.; Cerny, R.L.; DiRusso, C.C.; Black, P.N.
    Overexpression of human fatty acid transport protein 2/very long chain acyl-CoA synthetase 1 (FATP2/Acsvl1) reveals distinct patterns of trafficking of exogenous fatty acids (2013), Biochem. Biophys. Res. Commun., 440, 743-748.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.2.1.3 ATP + a long-chain fatty acid + CoA Homo sapiens
-
 AMP + diphosphate + a long-chain fatty acyl-CoA
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.2.1.3 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.2.1.3 HEK-293 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.2.1.3 ATP + a long-chain fatty acid + CoA
-
 Homo sapiens AMP + diphosphate + a long-chain fatty acyl-CoA
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.2.1.3 Acsvl1
-
 Homo sapiens
6.2.1.3 FATP2
-
 Homo sapiens
6.2.1.3 fatty acid transport protein 2
-
 Homo sapiens
6.2.1.3 very long chain acyl-CoA synthetase 1
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
6.2.1.3 ATP
-
 Homo sapiens

General Information

EC Number General Information Comment Organism
6.2.1.3 metabolism the expression of FATP2 slightly, but reproducibly, increases both C16:0-CoA and C20:4-CoA derived from exogenous fatty acids, the formation of acyl CoA from C18:3 and C22:6 is significant Homo sapiens
6.2.1.3 physiological function the enzyme plays a dual role in the transport and activation of exogenous fatty acids Homo sapiens