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Literature summary extracted from

  • Lindemann, A.; Pessi, G.; Schaefer, A.L.; Mattmann, M.E.; Christensen, Q.H.; Kessler, A.; Hennecke, H.; Blackwell, H.E.; Greenberg, E.P.; Harwood, C.S.
    Isovaleryl-homoserine lactone, an unusual branched-chain quorum-sensing signal from the soybean symbiont Bradyrhizobium japonicum (2011), Proc. Natl. Acad. Sci. USA, 108, 16765-16770.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.228 isovaleryl-CoA + S-adenosyl-L-methionine Bradyrhizobium japonicum enzyme requires S-adenosyl-L-methionine and isovaleryl-CoA as substrates for N-isovaleryl-L-homoserine lactone synthesis CoA + S-methyl-5'-thioadenosine + N-isovaleryl-L-homoserine lactone
-
 ?
2.3.1.228 isovaleryl-CoA + S-adenosyl-L-methionine Bradyrhizobium japonicum USDA 110 enzyme requires S-adenosyl-L-methionine and isovaleryl-CoA as substrates for N-isovaleryl-L-homoserine lactone synthesis CoA + S-methyl-5'-thioadenosine + N-isovaleryl-L-homoserine lactone
-
 ?
2.3.1.228 additional information Bradyrhizobium japonicum no substrate: isovaleryl-ACP ?
-
 ?
2.3.1.228 additional information Bradyrhizobium japonicum USDA 110 no substrate: isovaleryl-ACP ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.228 Bradyrhizobium japonicum Q89VI2
-
-
2.3.1.228 Bradyrhizobium japonicum USDA 110 Q89VI2
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.228 33
-
 pH 7.5, 37°C Bradyrhizobium japonicum

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.228 isovaleryl-CoA + S-adenosyl-L-methionine enzyme requires S-adenosyl-L-methionine and isovaleryl-CoA as substrates for N-isovaleryl-L-homoserine lactone synthesis Bradyrhizobium japonicum CoA + S-methyl-5'-thioadenosine + N-isovaleryl-L-homoserine lactone
-
 ?
2.3.1.228 isovaleryl-CoA + S-adenosyl-L-methionine enzyme requires S-adenosyl-L-methionine and isovaleryl-CoA as substrates for N-isovaleryl-L-homoserine lactone synthesis Bradyrhizobium japonicum USDA 110 CoA + S-methyl-5'-thioadenosine + N-isovaleryl-L-homoserine lactone
-
 ?
2.3.1.228 additional information no substrate: isovaleryl-ACP Bradyrhizobium japonicum ?
-
 ?
2.3.1.228 additional information no substrate: isovaleryl-ACP Bradyrhizobium japonicum USDA 110 ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.228 Bjal
-
 Bradyrhizobium japonicum

Expression

EC Number Organism Comment Expression
2.3.1.228 Bradyrhizobium japonicum presence of isovaleryl-homoserrine lactone induces the expression up