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Literature summary extracted from

  • de Freitas, A.S.; Rocha, J.B.
    Diphenyl diselenide and analogs are substrates of cerebral rat thioredoxin reductase: a pathway for their neuroprotective effects (2011), Neurosci. Lett., 503, 1-5.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.8.1.9 thioredoxin disulfide + NADPH + H+ Rattus norvegicus
-
 thioredoxin + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.8.1.9 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.8.1.9 brain
-
 Rattus norvegicus
-
1.8.1.9 cerebrum
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.1.9 4,4'-bischloro-diphenyl diselenide + NADPH + H+
-
 Rattus norvegicus ?
-
 ?
1.8.1.9 4,4'-bismethoxy-diphenyl diselenide + NADPH + H+
-
 Rattus norvegicus ?
-
 ?
1.8.1.9 diphenyl diselenide + NADPH + H+
-
 Rattus norvegicus ?
-
 ?
1.8.1.9 additional information ebselen, 4,4'-bistrifluoromethyl-diphenyl diselenide, 2,4,6,2',4',6‘-hexamethyldiphenyl diselenide, and 4,4'-biscarboxydiphenyl diselenide are no substrates Rattus norvegicus ?
-
 ?
1.8.1.9 thioredoxin disulfide + NADPH + H+
-
 Rattus norvegicus thioredoxin + NADP+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.8.1.9 TrxR
-
 Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.8.1.9 NADPH
-
 Rattus norvegicus