Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Kurogi, K.; Krasowski, M.D.; Injeti, E.; Liu, M.Y.; Williams, F.E.; Sakakibara, Y.; Suiko, M.; Liu, M.C.
    A comparative study of the sulfation of bile acids and a bile alcohol by the Zebra danio (Danio rerio) and human cytosolic sulfotransferases (SULTs) (2011), J. Steroid Biochem. Mol. Biol., 127, 307-314.
    View publication on PubMedView publication on EuropePMC

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.8.2.14 0.00836
-
 lithocholate in 50 mM Mops buffer at pH 7.0, at 37°C Homo sapiens
2.8.2.14 0.03673
-
 glycochenodeoxycholate in 50 mM Mops buffer at pH 7.0, at 37°C Homo sapiens
2.8.2.14 0.0423
-
 chenodeoxycholate in 50 mM Mops buffer at pH 7.0, at 37°C Homo sapiens
2.8.2.14 0.04938
-
 Petromyzonol in 50 mM Mops buffer at pH 7.0, at 37°C Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.8.2.14 cytosol
-
 Homo sapiens 5829
-

Organism

EC Number Organism UniProt Comment Textmining
2.8.2.14 Homo sapiens
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.8.2.14 0.00079
-
 using hyodeoxycholate as substrate, in 50 mM Mops buffer at pH 7.0, at 37°C Homo sapiens
2.8.2.14 0.00248
-
 using allochloate as substrate, in 50 mM Mops buffer at pH 7.0, at 37°C Homo sapiens
2.8.2.14 0.00248
-
 using taurochenodeoxycholate as substrate, in 50 mM Mops buffer at pH 7.0, at 37°C Homo sapiens
2.8.2.14 0.0028
-
 using glycochenodeoxycholate as substrate, in 50 mM Mops buffer at pH 7.0, at 37°C Homo sapiens
2.8.2.14 0.00354
-
 using chenodeoxycholate as substrate, in 50 mM Mops buffer at pH 7.0, at 37°C Homo sapiens
2.8.2.14 0.00359
-
 using petromyzonol as substrate, in 50 mM Mops buffer at pH 7.0, at 37°C Homo sapiens
2.8.2.14 0.00492
-
 using ursodeoxycholate as substrate, in 50 mM Mops buffer at pH 7.0, at 37°C Homo sapiens
2.8.2.14 0.00819
-
 using deoxycholate as substrate, in 50 mM Mops buffer at pH 7.0, at 37°C Homo sapiens
2.8.2.14 0.02361
-
 using lithocholate as substrate, in 50 mM Mops buffer at pH 7.0, at 37°C Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.2.14 3'-phosphoadenylyl-sulfate + allocholate
-
 Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 ?
2.8.2.14 3'-phosphoadenylyl-sulfate + chenodeoxycholate
-
 Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 ?
2.8.2.14 3'-phosphoadenylyl-sulfate + deoxycholate
-
 Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 ?
2.8.2.14 3'-phosphoadenylyl-sulfate + glycochenodeoxycholate
-
 Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 ?
2.8.2.14 3'-phosphoadenylyl-sulfate + hyodeoxycholate
-
 Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 ?
2.8.2.14 3'-phosphoadenylyl-sulfate + lithocholate best substrate Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 ?
2.8.2.14 3'-phosphoadenylyl-sulfate + petromyzonol
-
 Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 ?
2.8.2.14 3'-phosphoadenylyl-sulfate + taurochenodeoxycholate
-
 Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 ?
2.8.2.14 3'-phosphoadenylyl-sulfate + ursodeoxycholate
-
 Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 ?
2.8.2.14 additional information no activity with glycocholic acid, taurocholic acid, and cholic acid Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.8.2.14 SULT2A1
-
 Homo sapiens

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.8.2.14 6.5 9
-
 Homo sapiens