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Literature summary extracted from

  • Mercer, N.A.; McKelvey, J.R.; Fioravanti, C.F.
    Hymenolepis diminuta: catalysis of transmembrane proton translocation by mitochondrial NADPH->NAD transhydrogenase (1999), Exp. Parasitol., 91, 52-58.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.6.1.3 carbonyl cyanide 3-chlorophenylhydrazone
-
 Hymenolepis diminuta
1.6.1.3 carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone
-
 Hymenolepis diminuta
1.6.1.3 niclosamide
-
 Hymenolepis diminuta

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.6.1.3 1,3-dicyclohexyl-1,3-diazapropa-1,2-diene
-
 Hymenolepis diminuta

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.6.1.3 mitochondrial inner membrane
-
 Hymenolepis diminuta 5743
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.6.1.3 NADPH + NAD+ Hymenolepis diminuta
-
 NADP+ + NADH
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.6.1.3 Hymenolepis diminuta
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.6.1.3 NADPH + NAD+
-
 Hymenolepis diminuta NADP+ + NADH
-
 r

Synonyms

EC Number Synonyms Comment Organism
1.6.1.3 mitochondrial NADPH->NAD transhydrogenase
-
 Hymenolepis diminuta

Cofactor

EC Number Cofactor Comment Organism Structure
1.6.1.3 NADPH
-
 Hymenolepis diminuta

General Information

EC Number General Information Comment Organism
1.6.1.3 physiological function the enzyme of adult Hymenolepis diminuta physiologically couples matrix-localized, NADP-specific malic enzyme with NADH-dependent anaerobic electron transport. The enzyme acts in the translocation of protons from the matrix to the intermembrane space mitochondrial compartment Hymenolepis diminuta