Literature summary extracted from

Murphy, T.R.; Vihtelic, T.S.; Ile, K.E.; Watson, C.T.; Willer, G.B.; Gregg, R.G.; Bankaitis, V.A.; Hyde, D.R.
Phosphatidylinositol synthase is required for lens structural integrity and photoreceptor cell survival in the zebrafish eye (2011), Exp. Eye Res., 93, 460-474.

Protein Variants

EC Number	Protein Variants	Comment	Organism
2.7.8.11	S111C	missense mutation leads to lens opaque (lop) phenotype. Mutation is located in the catalytic domain of the 213 amino acid phosphatidylinositol (PI) synthase enzyme	Danio rerio

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.8.11	Danio rerio	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining

Synonyms

EC Number	Synonyms	Comment	Organism
2.7.8.11	cdipt	-	Danio rerio
2.7.8.11	CDP-diacylglycerol-inositol 3-phosphatidyltransferase	-	Danio rerio

General Information

EC Number	General Information	Comment	Organism
2.7.8.11	malfunction	using a cdipt knockout it shown that cdipt is required for lens structural integrity and photoreceptor cell survival in the zebrafish eye	Danio rerio

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Release 2023.1 (January 2023)