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Literature summary extracted from

  • Koma, D.; Yamanaka, H.; Moriyoshi, K.; Ohmoto, T.; Sakai, K.
    Production of aromatic compounds by metabolically engineered Escherichia coli with an expanded shikimate pathway (2012), Appl. Environ. Microbiol., 78, 6203-6216.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.39 4-hydroxyphenylacetaldehyde + NAD+ + H2O Escherichia coli
-
 4-hydroxyphenylacetate + NADH + H+
-
 ?
1.2.1.39 phenylacetaldehyde + NAD+ + H2O Escherichia coli
-
 phenylacetate + NADH + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.39 Escherichia coli P80668 BW25113
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.39 4-hydroxyphenylacetaldehyde + NAD+ + H2O
-
 Escherichia coli 4-hydroxyphenylacetate + NADH + H+
-
 ?
1.2.1.39 phenylacetaldehyde + NAD+ + H2O
-
 Escherichia coli phenylacetate + NADH + H+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.2.1.39 feaB
-
 Escherichia coli
1.2.1.39 PAAL dehydrogenase
-
 Escherichia coli

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.39 NAD+
-
 Escherichia coli

General Information

EC Number General Information Comment Organism
1.2.1.39 malfunction deletion of feaB gene results in increased desired aromatic compounds with decreased by-products. 2-Phenylethanol is not degraded by a feaB-deficient strain Escherichia coli