Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Moriya, S.; Iwasaki, K.; Samejima, K.; Takao, K.; Kohda, K.; Hiramatsu, K.; Kawakita, M.
    A mass spectrometric method to determine activities of enzymes involved in polyamine catabolism (2012), Anal. Chim. Acta, 748, 45-52.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.5.3.13 expression in HEK-293 cells Homo sapiens
1.5.3.16 expression in HEK-293 cells Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.5.3.13 MDL72527
-
 Homo sapiens
1.5.3.16 N1,N4-bis(2,3-butadienyl)-1,4-butanediamine i.e. MDL72527, partial inhibition Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.5.3.13 N1-acetylspermidine + O2 + H2O Homo sapiens
-
 putrescine + 3-acetamidopropanal + H2O2
-
 ?
1.5.3.13 N1-acetylspermine + O2 + H2O Homo sapiens
-
 spermidine + 3-acetamidopropanal + H2O2
-
 ?
1.5.3.16 spermine + O2 + H2O Homo sapiens
-
 spermidine + 3-aminopropanal + H2O2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.5.3.13 Homo sapiens
-
-
-
1.5.3.16 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.5.3.13 commercial preparation
-
 Homo sapiens
-
1.5.3.16 commercial preparation
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.3.13 additional information assay method development and validation, evaluation of quantitative determination of reaction products, overview Homo sapiens ?
-
 ?
1.5.3.13 N1,N11-didansylnorspermine + O2 + H2O
-
 Homo sapiens ? + H2O2
-
 ?
1.5.3.13 N1-acetylspermidine + O2 + H2O
-
 Homo sapiens putrescine + 3-acetamidopropanal + H2O2
-
 ?
1.5.3.13 N1-acetylspermine + O2 + H2O
-
 Homo sapiens spermidine + 3-acetamidopropanal + H2O2
-
 ?
1.5.3.16 additional information assay method development and validation, evaluation of quantitative determination of reaction products, overview Homo sapiens ?
-
 ?
1.5.3.16 spermine + O2 + H2O
-
 Homo sapiens spermidine + 3-aminopropanal + H2O2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.5.3.13 APAO
-
 Homo sapiens
1.5.3.16 SMO
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.5.3.13 37
-
 assay at Homo sapiens
1.5.3.16 37
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.5.3.13 9
-
 assay at Homo sapiens
1.5.3.16 9
-
 assay at Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.5.3.13 FAD dependent on Homo sapiens

General Information

EC Number General Information Comment Organism
1.5.3.13 metabolism the enzyme is involved in polyamine catabolic pathways, overview Homo sapiens
1.5.3.13 additional information method development for determination of polyamines and acetylpolyamines in the polyamine catabolic pathway creating heptafluorobutyryl derivatives of the compounds for TOF and hybrid tandem mass spectrometry, overview Homo sapiens
1.5.3.16 metabolism the enzyme is involved in polyamine catabolic pathways, overview Homo sapiens
1.5.3.16 additional information method development for determination of polyamines and acetylpolyamines in the polyamine catabolic pathway creating heptafluorobutyryl derivatives of the compounds for TOF and hybrid tandem mass spectrometry, overview Homo sapiens