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Literature summary extracted from

  • Duncan, T.; Trewick, S.C.; Koivisto, P.; Bates, P.A.; Lindahl, T.; Sedgwick, B.
    Reversal of DNA alkylation damage by two human dioxygenases (2002), Proc. Natl. Acad. Sci. USA, 99, 16660-5.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.11.33 cytoplasm diffuse presence of YFP-ABH3 construct Homo sapiens 5737
-
1.14.11.33 nucleolus accumulation of YFP-ABH2 construct Homo sapiens 5730
-
1.14.11.33 nucleoplasm diffuse presence of YFP-ABH2 construct Homo sapiens 5654
-
1.14.11.33 nucleus diffuse presence of YFP-ABH3 construct Homo sapiens 5634
-

Organism

EC Number Organism UniProt Comment Textmining
1.14.11.33 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.11.33 bladder high ABH2 and ABH3 mRNA levels Homo sapiens
-
1.14.11.33 colon high ABH3 mRNA levels Homo sapiens
-
1.14.11.33 HeLa cell high ABH2 mRNA levels Homo sapiens
-
1.14.11.33 liver high ABH2 mRNA levels Homo sapiens
-
1.14.11.33 prostate gland high ABH3 mRNA levels Homo sapiens
-
1.14.11.33 spleen high ABH3 mRNA levels Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.11.33 1-ethyladenine + O2 + 2-oxoglutarate
-
 Homo sapiens adenine + CO2 + acetaldehyde + succinate + H+
-
 ?
1.14.11.33 1-methyladenine + O2 + 2-oxoglutarate
-
 Homo sapiens adenine + CO2 + formaldehyde + succinate + H+
-
 ?
1.14.11.33 3-methylcytosine + O2 + 2-oxoglutarate
-
 Homo sapiens cytosine + CO2 + formaldehyde + succinate + H+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.11.33 ABH2
-
 Homo sapiens
1.14.11.33 ABH3
-
 Homo sapiens