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Literature summary extracted from

  • Walia, G.; Surolia, A.
    Insights into the regulatory characteristics of the mycobacterial dephosphocoenzyme A kinase: implications for the universal CoA biosynthesis pathway (2011), PLoS ONE, 6, e21390.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.24 CTP enzymatic activity is regulated by CTP which strongly binds the enzyme at a site overlapping that of the leading substrate, dephosphocoenzyme A, thereby obscuring the binding site and limiting catalysis. 16% residual activity at 1 mM CTP Mycobacterium tuberculosis

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.1.24 47000
-
 3 * 47000, SDS-PAGE Mycobacterium tuberculosis
2.7.1.24 141000
-
 gel filtration Mycobacterium tuberculosis

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.24 Mycobacterium tuberculosis
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.24 ATP + 3'-dephospho-CoA
-
 Mycobacterium tuberculosis ADP + CoA
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.1.24 homotrimer 3 * 47000, SDS-PAGE Mycobacterium tuberculosis

Synonyms

EC Number Synonyms Comment Organism
2.7.1.24 CoaE
-
 Mycobacterium tuberculosis
2.7.1.24 dephosphocoenzyme A kinase
-
 Mycobacterium tuberculosis