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Literature summary extracted from

  • Hohn, M.J.; Palioura, S.; Su, D.; Yuan, J.; Soell, D.
    Genetic analysis of selenocysteine biosynthesis in the archaeon Methanococcus maripaludis (2011), Mol. Microbiol., 81, 249-258.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
2.9.1.2 Methanococcus maripaludis Q6LZM9
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Synonyms

EC Number Synonyms Comment Organism
2.9.1.2 SelA
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 Methanococcus maripaludis

General Information

EC Number General Information Comment Organism
2.9.1.2 physiological function Methanococcus maripaludis Mm900 is facultatively selenium-dependent with a single pathway of Sec-tRNASec formation. Seelenocysteine formation is abolished upon individually deleting the genes encoding selenophosphate synthetase, phosphoseryl-tRNASec kinase, or SepSecS. The resulting mutant strains can no longer grow on formate while growth with H2 + CO2 remains unaffected. Deletion of the phosphoseryl-tRNASec kinase and SepSecS genes is not possible unless the selenium-free [NiFe]-hydrogenases Frc and Vhc are expressed Methanococcus maripaludis