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Literature summary extracted from

  • McGowan, S.J.; Sebaihia, M.; Porter, L.E.; Stewart, G.S.; Williams, P.; Bycroft, B.W.; Salmond, G.P.
    Analysis of bacterial carbapenem antibiotic production genes reveals a novel beta-lactam biosynthesis pathway (1996), Mol. Microbiol., 22, 415-426.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.20.3 expression in Escherichia coli Pectobacterium carotovorum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.226 malonyl-CoA + (S)-1-pyrroline-5-carboxylate + H2O Pectobacterium carotovorum
-
 CoA + (2S,5S)-5-carboxymethylproline + CO2
-
 ?
2.3.1.226 malonyl-CoA + (S)-1-pyrroline-5-carboxylate + H2O Pectobacterium carotovorum GS101
-
 CoA + (2S,5S)-5-carboxymethylproline + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.20.3 Pectobacterium carotovorum
-
-
-
2.3.1.226 Pectobacterium carotovorum
-
-
-
2.3.1.226 Pectobacterium carotovorum GS101
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.226 malonyl-CoA + (S)-1-pyrroline-5-carboxylate + H2O
-
 Pectobacterium carotovorum CoA + (2S,5S)-5-carboxymethylproline + CO2
-
 ?
2.3.1.226 malonyl-CoA + (S)-1-pyrroline-5-carboxylate + H2O
-
 Pectobacterium carotovorum GS101 CoA + (2S,5S)-5-carboxymethylproline + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.226 CarB
-
 Pectobacterium carotovorum