EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.5.1.74 | (R)-1-(4-((3-((4-chlorophenyl)(methoxyimino)methyl)phenoxy)-methyl)piperidin-1-yl)octan-2-yl carbamate | MIC value for Mycobacterium tuberculosis 0.0023 mg/ml | Mycobacterium tuberculosis | |
2.5.1.74 | (R)-1-(4-((3-(4-chlorobenzoyl)phenoxy)methyl)piperidin-1-yl)-octan-2-yl carbamate | MIC value for Mycobacterium tuberculosis 0.0023 mg/ml | Mycobacterium tuberculosis | |
2.5.1.74 | (S)-(2-chloro-4-((1-(2-hydroxyoctyl)piperidin-4-yl)methoxy)-phenyl)(4-chlorophenyl)methanone | MIC value for Mycobacterium tuberculosis 0.0015 mg/ml | Mycobacterium tuberculosis | |
2.5.1.74 | (S)-1-(4-((3-chloro-4-((4-chlorophenyl)(methoxyimino)methyl)-phenoxy)methyl)piperidin-1-yl)octan-2-yl carbamate | MIC value for Mycobacterium tuberculosis 0.0015 mg/ml | Mycobacterium tuberculosis | |
2.5.1.74 | (S)-1-(4-((3-chloro-4-(4-chlorobenzoyl)phenoxy)methyl)-piperidin-1-yl)octan-2-yl carbamate | MIC value for Mycobacterium tuberculosis 0.0015 mg/ml | Mycobacterium tuberculosis |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.5.1.74 | Mycobacterium tuberculosis | - |
- |
- |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
2.5.1.74 | 0.0012 | - |
pH 8.0, 37°C | Mycobacterium tuberculosis | (R)-1-(4-((3-((4-chlorophenyl)(methoxyimino)methyl)phenoxy)-methyl)piperidin-1-yl)octan-2-yl carbamate | |
2.5.1.74 | 0.0015 | - |
pH 8.0, 37°C | Mycobacterium tuberculosis | (R)-1-(4-((3-(4-chlorobenzoyl)phenoxy)methyl)piperidin-1-yl)-octan-2-yl carbamate | |
2.5.1.74 | 0.0015 | - |
pH 8.0, 37°C | Mycobacterium tuberculosis | (S)-1-(4-((3-chloro-4-(4-chlorobenzoyl)phenoxy)methyl)-piperidin-1-yl)octan-2-yl carbamate | |
2.5.1.74 | 0.0015 | - |
pH 8.0, 37°C | Mycobacterium tuberculosis | (S)-1-(4-((3-chloro-4-((4-chlorophenyl)(methoxyimino)methyl)-phenoxy)methyl)piperidin-1-yl)octan-2-yl carbamate | |
2.5.1.74 | 0.0035 | - |
pH 8.0, 37°C | Mycobacterium tuberculosis | (S)-(2-chloro-4-((1-(2-hydroxyoctyl)piperidin-4-yl)methoxy)-phenyl)(4-chlorophenyl)methanone |