EC Number | Cloned (Comment) | Organism |
---|---|---|
2.4.2.12 | - |
Homo sapiens |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
2.4.2.12 | H247A | active site residue, no detectable activity | Homo sapiens |
2.4.2.12 | H247E | active site residue, low activity | Homo sapiens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.4.2.12 | FK-866 | i.e. (2E)-N-[4-(1-benzoylpiperidin-4-yl)butyl]-3-phenylprop-2-enamide | Homo sapiens |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.4.2.12 | 55520 | - |
2 * 55520, theoretic value | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.2.12 | Homo sapiens | P43490 | - |
- |
EC Number | Posttranslational Modification | Comment | Organism |
---|---|---|---|
2.4.2.12 | phosphoprotein | autophosphorylation can increase the activity | Homo sapiens |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.4.2.12 | brain | - |
Homo sapiens | - |
2.4.2.12 | heart | - |
Homo sapiens | - |
2.4.2.12 | kidney | - |
Homo sapiens | - |
2.4.2.12 | liver | - |
Homo sapiens | - |
2.4.2.12 | lung | - |
Homo sapiens | - |
2.4.2.12 | lymphocyte | - |
Homo sapiens | - |
2.4.2.12 | pancreas | - |
Homo sapiens | - |
2.4.2.12 | placenta | - |
Homo sapiens | - |
2.4.2.12 | skeletal muscle | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.2.12 | nicotinamide + 5-phosphoribosyl 1-diphosphate | - |
Homo sapiens | nicotinamide mononucleotide + diphosphate | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.4.2.12 | homodimer | 2 * 55520, theoretic value | Homo sapiens |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.4.2.12 | nicotinamide phosphoribosyltransferase | - |
Homo sapiens |
2.4.2.12 | pre-B-cell colony enhancing factor | - |
Homo sapiens |
2.4.2.12 | Visfatin | - |
Homo sapiens |
EC Number | Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|---|
2.4.2.12 | Homo sapiens | theoretic value | - |
6.69 |
EC Number | General Information | Comment | Organism |
---|---|---|---|
2.4.2.12 | malfunction | implicated in the pathogenesis of a number of human diseases or conditions such as acute lung injury, aging, atherosclerosis, cancer, diabetes, rheumatoid arthritis and sepsis | Homo sapiens |
2.4.2.12 | physiological function | growth factor, cytokine and nicotinamide phosphoribosyltransferase | Homo sapiens |