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Literature summary extracted from

  • Juncosa, J.I.; Groves, A.P.; Xia, G.; Silverman, R.B.
    Probing the steric requirements of the gamma-aminobutyric acid aminotransferase active site with fluorinated analogues of vigabatrin (2013), Bioorg. Med. Chem., 21, 903-911.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.6.1.19 vigabatrin
-
 Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.6.1.19 2.2
-
 4-aminobutanoate pH 8.6, temperature not specified in the publication Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.19 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.6.1.19 brain
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.19 4-aminobutanoate + 2-oxoglutarate
-
 Sus scrofa 4-oxobutanoate + L-glutamate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.6.1.19 GABA-AT
-
 Sus scrofa
2.6.1.19 gamma-aminobutyric acid aminotransferase
-
 Sus scrofa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.6.1.19 8.6
-
 assay at Sus scrofa