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Literature summary extracted from

  • Zou, Y.; Wang, W.; Cai, L.; Chen, L.; Xue, M.; Zhang, X.; Shen, J.; Chen, M.
    Substrate specificity of galactokinase from Streptococcus pneumoniae TIGR4 towards galactose, glucose, and their derivatives (2012), Bioorg. Med. Chem. Lett., 22, 3540-3543.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.1.6 expressed in Escherichia coli Streptococcus pneumoniae

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.1.6 15.76
-
 N-acetyl-D-galactosamine pH 8.0, 45°C Streptococcus pneumoniae
2.7.1.6 37.23
-
 D-galactose pH 8.0, 45°C Streptococcus pneumoniae
2.7.1.6 49.37
-
 D-glucose pH 8.0, 45°C Streptococcus pneumoniae

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.1.6 37000
-
 calculatd from cDNA Streptococcus pneumoniae

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.6 Streptococcus pneumoniae
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.6 ATP + D-galactose
-
 Streptococcus pneumoniae ADP + alpha-D-galactose 1-phosphate
-
 ?
2.7.1.6 ATP + D-glucose
-
 Streptococcus pneumoniae ADP + alpha-D-glucose 1-phosphate
-
 ?
2.7.1.6 ATP + N-acetyl-D-galactosamine
-
 Streptococcus pneumoniae ADP + N-acetyl-alpha-D-galactosamine 1-phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.6 galactokinase
-
 Streptococcus pneumoniae
2.7.1.6 GalKSpe4
-
 Streptococcus pneumoniae

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.1.6 45
-
-
 Streptococcus pneumoniae

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
2.7.1.6 55
-
 nearly inactive at 55°C Streptococcus pneumoniae

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2.7.1.6 0.36
-
 N-acetyl-D-galactosamine pH 8.0, 45°C Streptococcus pneumoniae
2.7.1.6 1.1
-
 D-glucose pH 8.0, 45°C Streptococcus pneumoniae
2.7.1.6 2.61
-
 D-galactose pH 8.0, 45°C Streptococcus pneumoniae

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.1.6 8
-
-
 Streptococcus pneumoniae

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.7.1.6 3 11
-
 Streptococcus pneumoniae

kcat/KM [mM/s]

EC Number kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
2.7.1.6 0.022
-
 N-acetyl-D-galactosamine pH 8.0, 45°C Streptococcus pneumoniae
2.7.1.6 0.023
-
 D-glucose pH 8.0, 45°C Streptococcus pneumoniae
2.7.1.6 0.07
-
 D-galactose pH 8.0, 45°C Streptococcus pneumoniae