Literature summary extracted from

Grover, A.; Katiyar, S.P.; Singh, S.K.; Dubey, V.K.; Sundar, D.
A leishmaniasis study: structure-based screening and molecular dynamics mechanistic analysis for discovering potent inhibitors of spermidine synthase (2012), Biochim. Biophys. Acta, 1824, 1476-1483.

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.5.1.16	Leishmania donovani	Q9GSR3	-	-

Subunits

EC Number	Subunits	Comment	Organism
2.5.1.16	More	tertiary structure homology modeling using the homologous X-ray crystallographic structure of spermidine synthase from Trypanosoma cruzi, molecular dynamics simulations, overview	Leishmania donovani

General Information

EC Number	General Information	Comment	Organism
2.5.1.16	additional information	ligand docking modeling using the tertiary structure model, overview	Leishmania donovani
2.5.1.16	physiological function	spermidine synthase is an important enzyme in the synthetic pathway of polyamines in the parasite, is an essential element for the survival of this protozoan	Leishmania donovani

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)