EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.4.2.1 | 0.53 | - |
guanosine | pH 7.0, 80°C | Thermus thermophilus | |
2.4.2.1 | 1.01 | - |
2'-deoxyguanosine | pH 7.0, 80°C | Thermus thermophilus | |
2.4.2.1 | 2.06 | - |
2'-deoxyinosine | pH 7.0, 80°C | Thermus thermophilus | |
2.4.2.1 | 2.08 | - |
Inosine | pH 7.0, 80°C | Thermus thermophilus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.4.2.1 | 25415 | - |
6 * 25415, calculated | Thermus thermophilus |
2.4.2.1 | 156000 | - |
sedimentation equilibrium anlysis | Thermus thermophilus |
EC Number | Organic Solvent | Comment | Organism |
---|---|---|---|
2.4.2.1 | 2-methyltetrahydrofuran | 50%, 25% residual activity | Thermus thermophilus |
2.4.2.1 | dimethyl sulfoxide | 50%, 25% residual activity | Thermus thermophilus |
2.4.2.1 | dimethylformamide | 50%, 30% residual activity | Thermus thermophilus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.2.1 | Thermus thermophilus | Q72IR2 | - |
- |
2.4.2.1 | Thermus thermophilus HB27 / ATCC BAA-163 / DSM 7039 | Q72IR2 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.2.1 | 2'-deoxyguanosine + phosphate | - |
Thermus thermophilus | guanine + 2-deoxy-alpha-D-ribose 1-phosphate | 22.5% phosphorolysis of substrate within 30 min | ? | |
2.4.2.1 | 2'-deoxyguanosine + phosphate | - |
Thermus thermophilus HB27 / ATCC BAA-163 / DSM 7039 | guanine + 2-deoxy-alpha-D-ribose 1-phosphate | 22.5% phosphorolysis of substrate within 30 min | ? | |
2.4.2.1 | 2'-deoxyinosine + phosphate | - |
Thermus thermophilus | hypoxanthine + 2-deoxy-alpha-D-ribose 1-phosphate | 40.5% phosphorolysis of substrate within 30 min | ? | |
2.4.2.1 | 2'-deoxyinosine + phosphate | - |
Thermus thermophilus HB27 / ATCC BAA-163 / DSM 7039 | hypoxanthine + 2-deoxy-alpha-D-ribose 1-phosphate | 40.5% phosphorolysis of substrate within 30 min | ? | |
2.4.2.1 | guanosine + phosphate | - |
Thermus thermophilus | guanine + alpha-D-ribose 1-phosphate | 8.7% phosphorolysis of substrate within 30 min | ? | |
2.4.2.1 | guanosine + phosphate | - |
Thermus thermophilus HB27 / ATCC BAA-163 / DSM 7039 | guanine + alpha-D-ribose 1-phosphate | 8.7% phosphorolysis of substrate within 30 min | ? | |
2.4.2.1 | inosine + phosphate | - |
Thermus thermophilus | hypoxanthine + alpha-D-ribose 1-phosphate | 19.1% phosphorolysis of substrate within 30 min | ? | |
2.4.2.1 | inosine + phosphate | - |
Thermus thermophilus HB27 / ATCC BAA-163 / DSM 7039 | hypoxanthine + alpha-D-ribose 1-phosphate | 19.1% phosphorolysis of substrate within 30 min | ? | |
2.4.2.1 | additional information | no substrate: acyclovir, benzimidazole, 2,6-diaminopurine | Thermus thermophilus | ? | - |
? | |
2.4.2.1 | additional information | no substrate: acyclovir, benzimidazole, 2,6-diaminopurine | Thermus thermophilus HB27 / ATCC BAA-163 / DSM 7039 | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.4.2.1 | hexamer | 6 * 25415, calculated | Thermus thermophilus |
EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.4.2.1 | 80 | - |
half-life 132 h | Thermus thermophilus |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.4.2.1 | 173 | - |
Inosine | pH 7.0, 80°C | Thermus thermophilus | |
2.4.2.1 | 296 | - |
guanosine | pH 7.0, 80°C | Thermus thermophilus | |
2.4.2.1 | 627 | - |
2'-deoxyinosine | pH 7.0, 80°C | Thermus thermophilus | |
2.4.2.1 | 830 | - |
2'-deoxyguanosine | pH 7.0, 80°C | Thermus thermophilus |
EC Number | kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.4.2.1 | 83.2 | - |
Inosine | pH 7.0, 80°C | Thermus thermophilus | |
2.4.2.1 | 304.3 | - |
2'-deoxyinosine | pH 7.0, 80°C | Thermus thermophilus | |
2.4.2.1 | 558.8 | - |
guanosine | pH 7.0, 80°C | Thermus thermophilus | |
2.4.2.1 | 822.5 | - |
2'-deoxyguanosine | pH 7.0, 80°C | Thermus thermophilus |