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Literature summary extracted from

  • Todd, J.; Post-Beittenmiller, D.; Jaworski, J.
    KCS1 encodes a fatty acid elongase 3-ketoacyl-CoA synthase affecting wax biosynthesis in Arabidopsis thaliana (1999), Plant J., 17, 119-130.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.199 membrane
-
 Arabidopsis thaliana 16020
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.199 58300
-
 x * 58300, calculated from amino acid sequence Arabidopsis thaliana

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.199 Arabidopsis thaliana
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.199 cotyledon
-
 Arabidopsis thaliana
-
2.3.1.199 flower
-
 Arabidopsis thaliana
-
2.3.1.199 leaf
-
 Arabidopsis thaliana
-
2.3.1.199 root
-
 Arabidopsis thaliana
-
2.3.1.199 seed
-
 Arabidopsis thaliana
-
2.3.1.199 stem
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.199 oleoyl-CoA + malonyl-CoA in contrast to stearic acid-CoA, oleic acid-CoA serves as a less suitable substrate for elongation Arabidopsis thaliana ?
-
 ?
2.3.1.199 stearoyl-CoA + malonyl-CoA
-
 Arabidopsis thaliana CoA + 3-oxo-eicosanoyl-CoA + CO2 major product ?

Subunits

EC Number Subunits Comment Organism
2.3.1.199 ? x * 58300, calculated from amino acid sequence Arabidopsis thaliana

Synonyms

EC Number Synonyms Comment Organism
2.3.1.199 3-ketoacyl-CoA synthase
-
 Arabidopsis thaliana
2.3.1.199 Fatty acid elongase
-
 Arabidopsis thaliana
2.3.1.199 Kcs1
-
 Arabidopsis thaliana

General Information

EC Number General Information Comment Organism
2.3.1.199 malfunction complete loss of KCS1 expression results in decreases of up to 80% in the levels of C26 to C30 wax alcohols and aldehydes, while smaller effects are observed on the major wax components, i.e. the C29 alkanes and C29 ketones on leaves, stems and siliques. The loss of KCS1 expression does not result in complete loss of any individual wax component or significantly decrease the total wax load Arabidopsis thaliana
2.3.1.199 physiological function the enzyme plays a role in wax biosynthesis and is involved in both, the decarbonylation and acyl-reduction wax synthesis pathways Arabidopsis thaliana