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Literature summary extracted from

  • Demorest, Z.L.; Li, M.; Harris, R.S.
    Phosphorylation directly regulates the intrinsic DNA cytidine deaminase activity of activation-induced deaminase and APOBEC3G protein (2011), J. Biol. Chem., 286, 26568-26575.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.5.4.B9 expression of activation-induced deaminase, i.e. AID, and APOBEC3G in Escherichia coli strain BW310 and in human HEK293T cells Mus musculus
3.5.4.B9 expression of activation-induced deaminase, i.e. AID, and APOBEC3G in Escherichia coli strain BW310 and in human HEK293T cells Homo sapiens

Protein Variants

EC Number Protein Variants Comment Organism
3.5.4.B9 E259Q site-directed mutagenesis Mus musculus
3.5.4.B9 additional information phospho-mimetic mutations inhibit DNA cytidine deaminase activity Mus musculus
3.5.4.B9 additional information phospho-mimetic mutations inhibit DNA cytidine deaminase activity Homo sapiens
3.5.4.B9 T218A site-directed mutagenesis Mus musculus
3.5.4.B9 T218E site-directed mutagenesis Mus musculus
3.5.4.B9 T27A site-directed mutagenesis Mus musculus
3.5.4.B9 T27E site-directed mutagenesis Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.5.4.B9 cytosol
-
 Mus musculus 5829
-
3.5.4.B9 cytosol
-
 Homo sapiens 5829
-

Organism

EC Number Organism UniProt Comment Textmining
3.5.4.B9 Homo sapiens
-
-
-
3.5.4.B9 Mus musculus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.5.4.B9 phosphoprotein phosphorylation directly regulates the intrinsic DNA cytidine deaminase activity of activation-induced deaminase and APOBEC3G protein Mus musculus
3.5.4.B9 phosphoprotein phosphorylation directly regulates the intrinsic DNA cytidine deaminase activity of activation-induced deaminase and APOBEC3G protein Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
3.5.4.B9 activation-induced deaminase
-
 Mus musculus
3.5.4.B9 activation-induced deaminase
-
 Homo sapiens
3.5.4.B9 APOBEC3G
-
 Mus musculus
3.5.4.B9 APOBEC3G
-
 Homo sapiens
3.5.4.B9 DNA cytidine deaminase
-
 Mus musculus
3.5.4.B9 DNA cytidine deaminase
-
 Homo sapiens
3.5.4.B9 More cf. EC 3.5.4.14 Mus musculus
3.5.4.B9 More cf. EC 3.5.4.5 Mus musculus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.5.4.B9 37
-
 assay at Mus musculus
3.5.4.B9 37
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.5.4.B9 7.6
-
 assay at Mus musculus
3.5.4.B9 7.6
-
 assay at Homo sapiens