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Literature summary extracted from

  • Hendrich, M.; Logan, M.; Andersson, K.; Arciero, D.; Lipscomb, J.; Hooper, A.
    The active site of hydroxylamine oxidoreductase from Nitrosomonas: Evidence for a new metal cluster in enzymes (1994), J. Am. Chem. Soc., 116, 11961-11968.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.7.2.6 cyanide active site inhibitor Nitrosomonas europaea
1.7.2.6 N2H4
-
 Nitrosomonas europaea
1.7.2.6 NH2OH
-
 Nitrosomonas europaea

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.7.2.6 63000
-
 3 * 63000 Nitrosomonas europaea

Organism

EC Number Organism UniProt Comment Textmining
1.7.2.6 Nitrosomonas europaea
-
-
-
1.7.2.6 Nitrosomonas europaea Schmidt
-
-
-

Oxidation Stability

EC Number Oxidation Stability Organism
1.7.2.6 the enzyme is inactivated by incubation of 1 mM enzyme with a 5fold excess of peroxide for 1 h. The enzyme is also inactivated in the presence of H2O2 Nitrosomonas europaea

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.7.2.6 hydroxylamine + ferricytochrome c + H2O
-
 Nitrosomonas europaea nitrite + ferrocytochrome c + H+
-
 ?
1.7.2.6 hydroxylamine + ferricytochrome c + H2O
-
 Nitrosomonas europaea Schmidt nitrite + ferrocytochrome c + H+
-
 ?

Subunits

EC Number Subunits Comment Organism
1.7.2.6 homotrimer 3 * 63000 Nitrosomonas europaea

Synonyms

EC Number Synonyms Comment Organism
1.7.2.6 HAO
-
 Nitrosomonas europaea
1.7.2.6 hydroxylamine oxidoreductase
-
 Nitrosomonas europaea

Cofactor

EC Number Cofactor Comment Organism Structure
1.7.2.6 heme the enzyme contains eight hemes per subunit, seven C-type cytochromes and one heme P460 Nitrosomonas europaea