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Literature summary extracted from
- Pa0148 from Pseudomonas aeruginosa catalyzes the deamination of adenine (2011), Biochemistry, 50, 6589-6597.
Crystallization (Commentary)
| EC Number | Crystallization (Comment) | Organism |
|---|---|---|
| 3.5.4.2 | X-ray structures of Pa0148 (Pseudomonas aeruginos) and AAur1117 (Arthrobacter aurescens) are determined and reveal nearly identical distorted (beta/alpha)8 barrels with a single zinc ion that is characteristic of members of the amidohydrolase superfamily | Pseudomonas aeruginosa |
| 3.5.4.2 | X-ray structures of Pa0148 (Pseudomonas aeruginos) and AAur1117 (Arthrobacter aurescens) are determined and reveal nearly identical distorted (beta/alpha)8 barrels with a single zinc ion that is characteristic of members of the amidohydrolase superfamily | Paenarthrobacter aurescens |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.5.4.2 | 0.025 | - |
adenine | pH and temperature not specified in the publication | Pseudomonas aeruginosa |  |
| 3.5.4.2 | 0.026 | - |
6-Chloropurine | pH and temperature not specified in the publication | Burkholderia sp. | |
| 3.5.4.2 | 0.056 | - |
6-Chloropurine | pH and temperature not specified in the publication | Alteromonas macleodii | |
| 3.5.4.2 | 0.07 | - |
2,6-diaminopurine | pH and temperature not specified in the publication | Alteromonas macleodii | |
| 3.5.4.2 | 0.088 | - |
N-6-methyladenine | pH and temperature not specified in the publication | Pseudomonas aeruginosa | |
| 3.5.4.2 | 0.09 | - |
N-6-methyladenine | pH and temperature not specified in the publication | Alteromonas macleodii | |
| 3.5.4.2 | 0.13 | - |
6-methoxypurine | pH and temperature not specified in the publication | Alteromonas macleodii | |
| 3.5.4.2 | 0.14 | - |
2,6-diaminopurine | pH and temperature not specified in the publication | Pseudomonas aeruginosa | |
| 3.5.4.2 | 0.14 | - |
6-methoxypurine | pH and temperature not specified in the publication | Burkholderia sp. | |
| 3.5.4.2 | 0.16 | - |
6-methoxypurine | pH and temperature not specified in the publication | Paenarthrobacter aurescens | |
| 3.5.4.2 | 0.17 | - |
adenine | pH and temperature not specified in the publication | Burkholderia sp. | |
| 3.5.4.2 | 0.2 | - |
adenine | pH and temperature not specified in the publication | Paenarthrobacter aurescens | |
| 3.5.4.2 | 0.2 | - |
adenine | pH and temperature not specified in the publication | Alteromonas macleodii | |
| 3.5.4.2 | 0.26 | - |
6-Chloropurine | pH and temperature not specified in the publication | Pseudomonas aeruginosa | |
| 3.5.4.2 | 0.27 | - |
6-methoxypurine | pH and temperature not specified in the publication | Pseudomonas aeruginosa | |
| 3.5.4.2 | 0.29 | - |
2,6-diaminopurine | pH and temperature not specified in the publication | Paenarthrobacter aurescens | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.5.4.2 | Alteromonas macleodii | - |
- |
- |
| 3.5.4.2 | Burkholderia sp. | - |
- |
- |
| 3.5.4.2 | Paenarthrobacter aurescens | - |
- |
- |
| 3.5.4.2 | Pseudomonas aeruginosa | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.5.4.2 | 2,6-diaminopurine + H2O | - |
Pseudomonas aeruginosa | ? | - |
? | |
| 3.5.4.2 | 2,6-diaminopurine + H2O | - |
Paenarthrobacter aurescens | ? | - |
? | |
| 3.5.4.2 | 2,6-diaminopurine + H2O | - |
Burkholderia sp. | ? | - |
? | |
| 3.5.4.2 | 2,6-diaminopurine + H2O | - |
Alteromonas macleodii | ? | - |
? | |
| 3.5.4.2 | 6-chloropurine + H2O | - |
Pseudomonas aeruginosa | hypoxanthine + HCl | - |
? | |
| 3.5.4.2 | 6-chloropurine + H2O | - |
Paenarthrobacter aurescens | hypoxanthine + HCl | - |
? | |
| 3.5.4.2 | 6-chloropurine + H2O | - |
Burkholderia sp. | hypoxanthine + HCl | - |
? | |
| 3.5.4.2 | 6-chloropurine + H2O | - |
Alteromonas macleodii | hypoxanthine + HCl | - |
? | |
| 3.5.4.2 | 6-methoxypurine + H2O | - |
Pseudomonas aeruginosa | ? | - |
? | |
| 3.5.4.2 | 6-methoxypurine + H2O | - |
Paenarthrobacter aurescens | ? | - |
? | |
| 3.5.4.2 | 6-methoxypurine + H2O | - |
Burkholderia sp. | ? | - |
? | |
| 3.5.4.2 | 6-methoxypurine + H2O | - |
Alteromonas macleodii | ? | - |
? | |
| 3.5.4.2 | adenine + H2O | - |
Pseudomonas aeruginosa | hypoxanthine + NH3 | - |
? | |
| 3.5.4.2 | adenine + H2O | - |
Paenarthrobacter aurescens | hypoxanthine + NH3 | - |
? | |
| 3.5.4.2 | adenine + H2O | - |
Burkholderia sp. | hypoxanthine + NH3 | - |
? | |
| 3.5.4.2 | adenine + H2O | - |
Alteromonas macleodii | hypoxanthine + NH3 | - |
? | |
| 3.5.4.2 | N-6-methyladenine + H2O | - |
Pseudomonas aeruginosa | ? | - |
? | |
| 3.5.4.2 | N-6-methyladenine + H2O | - |
Paenarthrobacter aurescens | ? | - |
? | |
| 3.5.4.2 | N-6-methyladenine + H2O | - |
Burkholderia sp. | ? | - |
? | |
| 3.5.4.2 | N-6-methyladenine + H2O | - |
Alteromonas macleodii | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.5.4.2 | AAur1117 | - |
Paenarthrobacter aurescens |
| 3.5.4.2 | Pa0148 | - |
Pseudomonas aeruginosa |
| 3.5.4.2 | Sgx9403e | - |
Alteromonas macleodii |
| 3.5.4.2 | Sgx9403g | - |
Burkholderia sp. |
Turnover Number [1/s]
| EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.5.4.2 | 0.42 | - |
6-Chloropurine | pH and temperature not specified in the publication | Burkholderia sp. | |
| 3.5.4.2 | 0.48 | - |
N-6-methyladenine | pH and temperature not specified in the publication | Alteromonas macleodii | |
| 3.5.4.2 | 0.52 | - |
6-methoxypurine | pH and temperature not specified in the publication | Alteromonas macleodii | |
| 3.5.4.2 | 0.84 | - |
6-Chloropurine | pH and temperature not specified in the publication | Alteromonas macleodii | |
| 3.5.4.2 | 1.28 | - |
N-6-methyladenine | pH and temperature not specified in the publication | Pseudomonas aeruginosa | |
| 3.5.4.2 | 1.8 | - |
2,6-diaminopurine | pH and temperature not specified in the publication | Alteromonas macleodii | |
| 3.5.4.2 | 1.9 | - |
6-Chloropurine | pH and temperature not specified in the publication | Pseudomonas aeruginosa | |
| 3.5.4.2 | 1.9 | - |
6-methoxypurine | pH and temperature not specified in the publication | Paenarthrobacter aurescens | |
| 3.5.4.2 | 2.2 | - |
6-methoxypurine | pH and temperature not specified in the publication | Burkholderia sp. | |
| 3.5.4.2 | 3 | 6 | adenine | pH and temperature not specified in the publication | Pseudomonas aeruginosa | |
| 3.5.4.2 | 6.9 | - |
2,6-diaminopurine | pH and temperature not specified in the publication | Paenarthrobacter aurescens | |
| 3.5.4.2 | 7.1 | - |
6-methoxypurine | pH and temperature not specified in the publication | Pseudomonas aeruginosa | |
| 3.5.4.2 | 17 | - |
2,6-diaminopurine | pH and temperature not specified in the publication | Pseudomonas aeruginosa | |
| 3.5.4.2 | 56 | - |
adenine | pH and temperature not specified in the publication | Burkholderia sp. | |
| 3.5.4.2 | 61 | - |
adenine | pH and temperature not specified in the publication | Paenarthrobacter aurescens | |
| 3.5.4.2 | 62 | - |
adenine | pH and temperature not specified in the publication | Alteromonas macleodii | |
kcat/KM [mM/s]
| EC Number | kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.5.4.2 | 1.3 | - |
N-6-methyladenine | pH and temperature not specified in the publication | Paenarthrobacter aurescens | |
| 3.5.4.2 | 1.6 | - |
N-6-methyladenine | pH and temperature not specified in the publication | Burkholderia sp. | |
| 3.5.4.2 | 4 | - |
6-methoxypurine | pH and temperature not specified in the publication | Alteromonas macleodii | |
| 3.5.4.2 | 5.3 | - |
N-6-methyladenine | pH and temperature not specified in the publication | Alteromonas macleodii | |
| 3.5.4.2 | 7.3 | - |
6-Chloropurine | pH and temperature not specified in the publication | Pseudomonas aeruginosa | |
| 3.5.4.2 | 9.6 | - |
6-Chloropurine | pH and temperature not specified in the publication | Paenarthrobacter aurescens | |
| 3.5.4.2 | 12 | - |
6-methoxypurine | pH and temperature not specified in the publication | Paenarthrobacter aurescens | |
| 3.5.4.2 | 15 | - |
6-Chloropurine | pH and temperature not specified in the publication | Alteromonas macleodii | |
| 3.5.4.2 | 15 | - |
N-6-methyladenine | pH and temperature not specified in the publication | Pseudomonas aeruginosa | |
| 3.5.4.2 | 16 | - |
6-Chloropurine | pH and temperature not specified in the publication | Burkholderia sp. | |
| 3.5.4.2 | 17 | - |
6-methoxypurine | pH and temperature not specified in the publication | Burkholderia sp. | |
| 3.5.4.2 | 19 | - |
2,6-diaminopurine | pH and temperature not specified in the publication | Burkholderia sp. | |
| 3.5.4.2 | 24 | - |
2,6-diaminopurine | pH and temperature not specified in the publication | Paenarthrobacter aurescens | |
| 3.5.4.2 | 26 | - |
6-methoxypurine | pH and temperature not specified in the publication | Pseudomonas aeruginosa | |
| 3.5.4.2 | 28 | - |
2,6-diaminopurine | pH and temperature not specified in the publication | Alteromonas macleodii | |
| 3.5.4.2 | 120 | - |
2,6-diaminopurine | pH and temperature not specified in the publication | Pseudomonas aeruginosa | |
| 3.5.4.2 | 310 | - |
adenine | pH and temperature not specified in the publication | Paenarthrobacter aurescens | |
| 3.5.4.2 | 330 | - |
adenine | pH and temperature not specified in the publication | Burkholderia sp. | |
| 3.5.4.2 | 1400 | - |
adenine | pH and temperature not specified in the publication | Pseudomonas aeruginosa | |
| 3.5.4.2 | 3100 | - |
adenine | pH and temperature not specified in the publication | Alteromonas macleodii | |
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