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Literature summary extracted from
- Preparation and characterization of cobalt-substituted anthrax lethal factor (2011), Biochem. Biophys. Res. Commun., 416, 106-110.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.4.24.83 | expressed in Bacillus megaterium | Bacillus anthracis |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.24.83 | Co2+ | Co2+ is capable of directly replacing lethal factors active site Zn2+ to yield a hyperactive enzyme with 2fold higher kcat value and about 2.5fold increased catalytic efficiency | Bacillus anthracis |  |
| 3.4.24.83 | Zn2+ | dependent on Zn2+, contains 0.03 mol Zn2+ per mol of protein | Bacillus anthracis | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.24.83 | Bacillus anthracis | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.24.83 | Q Sepharose column chromatography and Superdex 200 gel filtration | Bacillus anthracis |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.24.83 | acetyl-Gly-Tyr-betaAla-RRRRRRRRVLR-4-nitroanilide + H2O | - |
Bacillus anthracis | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.24.83 | anthrax lethal factor | - |
Bacillus anthracis |
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Release 2023.1 (January 2023)
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