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Literature summary extracted from

  • Sun, T.; Hayakawa, K.; Fraser, M.E.
    ADP-Mg2+ bound to the ATP-grasp domain of ATP-citrate lyase (2011), Acta Crystallogr. Sect. F, 67, 1168-1172.
    View publication on PubMedView publication on EuropePMC

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.3.3.8 tartrate and ADP-Mg2+ bound N-terminal portion of the enzyme containing residues 1-817, hanging drop vapor diffusion method, using 12.5% (w/v) polyethylene glycol 3350, 125 mM sodium tartrate, 100 mM Tris-HCl (pH 8.2) Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.3.8 Tartrate
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.3.8 cytoplasm
-
 Homo sapiens 5737
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.3.3.8 Mg2+ required Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.3.3.8 Homo sapiens P53396
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.3.8 immobilized metal-ion affinity chromatography Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.3.8 ATP + citrate + CoA
-
 Homo sapiens ADP + phosphate + acetyl-CoA + oxaloacetate
-
 ir

Synonyms

EC Number Synonyms Comment Organism
2.3.3.8 ACLY
-
 Homo sapiens
2.3.3.8 ATP-citrate lyase
-
 Homo sapiens