EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.1.132 | (2Z,4Z)-2-hydroxyhexa-2,4-dienoic acid + H2O | Comamonas testosteroni | 2-hydroxyhexa-2,4-dienoic acid is an intermediate of testosterone degradation | 4-hydroxy-2-oxohexanoic acid | - |
? | |
4.2.1.132 | (2Z,4Z)-2-hydroxyhexa-2,4-dienoic acid + H2O | Comamonas testosteroni TA441 | 2-hydroxyhexa-2,4-dienoic acid is an intermediate of testosterone degradation | 4-hydroxy-2-oxohexanoic acid | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.2.1.132 | Comamonas testosteroni | - |
formerly Pseudomonas testosteroni, gene tesE | - |
4.2.1.132 | Comamonas testosteroni TA441 | - |
formerly Pseudomonas testosteroni, gene tesE | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.1.132 | (2Z,4Z)-2-hydroxyhexa-2,4-dienoic acid + H2O | 2-hydroxyhexa-2,4-dienoic acid is an intermediate of testosterone degradation | Comamonas testosteroni | 4-hydroxy-2-oxohexanoic acid | - |
? | |
4.2.1.132 | (2Z,4Z)-2-hydroxyhexa-2,4-dienoic acid + H2O | i.e. X5P-1, stable in enol form in methanol solution | Comamonas testosteroni | 4-hydroxy-2-oxohexanoic acid | - |
? | |
4.2.1.132 | (2Z,4Z)-2-hydroxyhexa-2,4-dienoic acid + H2O | 2-hydroxyhexa-2,4-dienoic acid is an intermediate of testosterone degradation | Comamonas testosteroni TA441 | 4-hydroxy-2-oxohexanoic acid | - |
? | |
4.2.1.132 | (2Z,4Z)-2-hydroxyhexa-2,4-dienoic acid + H2O | i.e. X5P-1, stable in enol form in methanol solution | Comamonas testosteroni TA441 | 4-hydroxy-2-oxohexanoic acid | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.2.1.132 | TesE | - |
Comamonas testosteroni |
EC Number | General Information | Comment | Organism |
---|---|---|---|
4.2.1.132 | metabolism | 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oic acid, 4-hydroxy-2-oxohexanoic acid, and 2-hydroxyhexa-2,4-dienoic acid and related enzymes are involved in testosterone degradation in strain TA441. The organism utilizes testosterone via aromatization of the A ring | Comamonas testosteroni |