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Literature summary extracted from

  • Nickens, D.G.; Bardiya, N.; Patterson, J.T.; Burke, D.H.
    Template-directed ligation of tethered mononucleotides by T4 DNA ligase for kinase ribozyme selection (2010), PLoS ONE, 5, e12368.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
6.5.1.1 Tequatrovirus T4
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-
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.5.1.1 ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m
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 Tequatrovirus T4 AMP + diphosphate + (deoxyribonucleotide)m+n
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 ?
6.5.1.1 additional information T4 DNA ligase is also able to capture RNA strands in which a tethered monodeoxynucleoside has acquired a 5' phosphate. The ligation reaction therefore mimics the partition step of a selection for nucleoside kinase (deoxy)ribozymes Tequatrovirus T4 ?
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 ?

Synonyms

EC Number Synonyms Comment Organism
6.5.1.1 T4 DNA ligase
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 Tequatrovirus T4

Cofactor

EC Number Cofactor Comment Organism Structure
6.5.1.1 ATP required Tequatrovirus T4