BRENDA - Enzyme Database show

Inhibition of delta-aminolevulinic acid dehydratase activity by cadmium in excised etiolated maize leaf segments during greening

Sarangthem, J.; Jain, M.; Gadre, R.; Plant Soil Environ. 57, 332-337 (2011)
No PubMed abstract available

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
4.2.1.24
Cd2+
enzyme inhibition in excised etiolated leaf segments during greening. Cd2+ inhibits ALAD activity by affecting the ALA bind­ing to the enzyme and/or disrupting thiol interaction. Inhibition of ALAD activity by Cd2+ is decreased in the presence of nitrogenous compounds, glutamine and NH4NO3, overview. Supply of some essential metal ions, such as Mg2+, Zn2+, and Mn2+, also reduces the inhibition of enzyme activity by Cd2+
Zea mays
4.2.1.24
GSH
a weak inhibitor
Zea mays
4.2.1.24
levulinic acid
a weak competitive inhibitor
Zea mays
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
4.2.1.24
Mg2+
activates
Zea mays
4.2.1.24
Mn2+
activates
Zea mays
4.2.1.24
Zn2+
activates
Zea mays
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.2.1.24
2 5-aminolevulinate
Zea mays
-
porphobilinogen + 2 H2O
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.2.1.24
Zea mays
-
cv. Ganga
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
4.2.1.24
leaf
etiolated
Zea mays
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.24
2 5-aminolevulinate
-
716637
Zea mays
porphobilinogen + 2 H2O
-
-
-
?
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
4.2.1.24
Cd2+
enzyme inhibition in excised etiolated leaf segments during greening. Cd2+ inhibits ALAD activity by affecting the ALA bind­ing to the enzyme and/or disrupting thiol interaction. Inhibition of ALAD activity by Cd2+ is decreased in the presence of nitrogenous compounds, glutamine and NH4NO3, overview. Supply of some essential metal ions, such as Mg2+, Zn2+, and Mn2+, also reduces the inhibition of enzyme activity by Cd2+
Zea mays
4.2.1.24
GSH
a weak inhibitor
Zea mays
4.2.1.24
levulinic acid
a weak competitive inhibitor
Zea mays
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
4.2.1.24
Mg2+
activates
Zea mays
4.2.1.24
Mn2+
activates
Zea mays
4.2.1.24
Zn2+
activates
Zea mays
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.2.1.24
2 5-aminolevulinate
Zea mays
-
porphobilinogen + 2 H2O
-
-
?
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
4.2.1.24
leaf
etiolated
Zea mays
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.24
2 5-aminolevulinate
-
716637
Zea mays
porphobilinogen + 2 H2O
-
-
-
?