EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
5.4.99.2 | Sus scrofa | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.4.99.2 | (R)-2-methylmalonyl-CoA | - |
Sus scrofa | succinyl-CoA | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
5.4.99.2 | MCM | - |
Sus scrofa |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
5.4.99.2 | adenosylcobalamin | - |
Sus scrofa |
EC Number | General Information | Comment | Organism |
---|---|---|---|
5.4.99.2 | physiological function | methylmalonyl-CoA mutase (MUT) expression influences the risk of acquiring Mycobacterium bovis infection and developing bovine tuberculosis. Genetically-defined higher host MUT expression levels result in lower serum cholesterol concentration and tissue deposits that increase the protective immune response to Mycobacterium bovis, thus resulting in resistance to bovine tuberculosis and better response to Mycobacterium bovis bacilli Calmette-Guerin vaccination | Sus scrofa |