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Literature summary extracted from

  • Lacampagne, S.; Gagne, S.; Geny, L.
    Involvement of abscisic acid in controlling the proanthocyanidin biosynthesis pathway in grape skin: new elements regarding the regulation of tannin composition and leucoanthocyanidin reductase (LAR) and anthocyanidin reductase (ANR) activities and expres (2010), J. Plant Growth Regul., 29, 81-90.
No PubMed abstract available

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.17.1.3 (2R,3S)-catechin + NADP+ + H2O Vitis vinifera
-
 2,3-trans-3,4-cis-leucocyanidin + NADPH + H+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.112 Vitis vinifera Q5FB34
-
-
1.17.1.3 Vitis vinifera
-
 cv. Cabernet-Sauvignon
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.1.112 fruit grape skin Vitis vinifera
-
1.17.1.3 fruit skin Vitis vinifera
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.17.1.3 (2R,3S)-catechin + NADP+ + H2O
-
 Vitis vinifera 2,3-trans-3,4-cis-leucocyanidin + NADPH + H+
-
 r

Synonyms

EC Number Synonyms Comment Organism
1.17.1.3 LAR
-
 Vitis vinifera

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.17.1.3 25
-
 assay at Vitis vinifera

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.17.1.3 7.5
-
 assay at Vitis vinifera

Cofactor

EC Number Cofactor Comment Organism Structure
1.17.1.3 NADPH
-
 Vitis vinifera

Expression

EC Number Organism Comment Expression
1.3.1.77 Vitis vinifera abscisic acid decreases ANR activity and represses the expression a few days after application down
1.3.1.112 Vitis vinifera trreatment with abscisic acid affects tannin content and is involved in the tannin biosynthesis pathway in grape skin by decreasing leucoanthocyanidin reductase and ANR activity and repressing the expression of related genes a few days after application down

General Information

EC Number General Information Comment Organism
1.17.1.3 metabolism leucoanthocyanidin reductase and anthocyanidin reductase are involved in biosynthesis of proanthocyanidins or condensed tannins by producing (+)-catechin and (-)-epicatechin, respectively, from leukoanthocyanidin Vitis vinifera
1.17.1.3 additional information leucoanthocyanidin reductase and anthocyanidin reductase are co-regulated by abscisic acid, overview Vitis vinifera