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Literature summary extracted from
- Involvement of NADPH in the cyclization reaction of carotenoid biosynthesis (2002), FEBS Lett., 515, 133-136.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.5.1.19 | NAD(P)H | absolutely required for cyclization reaction. No hydrogen is transferred from NADPH, which is therefore not involved directly in the cyclization reaction, but must play an indirect role, e.g. as an allosteric activator | Pantoea ananatis |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.5.1.19 | Pantoea ananatis | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 5.5.1.19 | - |
Pantoea ananatis |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.5.1.19 | lycopene | the hydrogen atom introduced at C(2) in the cyclization comes from water and not from NADPH. The mechanism involves the initiation of cyclization by H+ attack at C(2) of the folded acyclic end group of the precursor | Pantoea ananatis | beta-carotene | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 5.5.1.19 | CrtY | - |
Pantoea ananatis |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 5.5.1.19 | 30 | - |
assay at | Pantoea ananatis |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 5.5.1.19 | 6.5 | - |
assay at | Pantoea ananatis |
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Release 2023.1 (January 2023)
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