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Literature summary extracted from

  • Saada, M.C.; Vullo, D.; Montero, J.L.; Scozzafava, A.; Winum, J.Y.; Supuran, C.T.
    Carbonic anhydrase I and II activation with mono- and dihalogenated histamine derivatives (2011), Bioorg. Med. Chem. Lett., 21, 4884-4887.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.2.1.1 2-(2,5-dibromo-1H-imidazol-4-yl)ethanamine
-
 Homo sapiens
4.2.1.1 2-(2,5-dichloro-1H-imidazol-4-yl)ethanamine
-
 Homo sapiens
4.2.1.1 2-(2,5-diiodo-1H-imidazol-4-yl)ethanamine
-
 Homo sapiens
4.2.1.1 2-(5-bromo-1H-imidazol-4-yl)ethanamine
-
 Homo sapiens
4.2.1.1 2-(5-chloro-1H-imidazol-4-yl)ethanamine
-
 Homo sapiens
4.2.1.1 2-(5-iodo-1H-imidazol-4-yl)ethanamine
-
 Homo sapiens
4.2.1.1 histamine
-
 Homo sapiens
4.2.1.1 additional information Ka values of activators of isozymes hCA I and hCA II, overview Homo sapiens
4.2.1.1 tert-butyl [2-(2,5-dibromo-1H-imidazol-4-yl)ethyl]carbamate
-
 Homo sapiens
4.2.1.1 tert-butyl [2-(2,5-dichloro-1H-imidazol-4-yl)ethyl]carbamate
-
 Homo sapiens
4.2.1.1 tert-butyl [2-(2,5-diiodo-1H-imidazol-4-yl)ethyl]carbamate
-
 Homo sapiens
4.2.1.1 tert-butyl [2-(5-bromo-1H-imidazol-4-yl)ethyl]carbamate
-
 Homo sapiens
4.2.1.1 tert-butyl [2-(5-chloro-1H-imidazol-4-yl)ethyl]carbamate
-
 Homo sapiens
4.2.1.1 tert-butyl [2-(5-iodo-1H-imidazol-4-yl)ethyl]carbamate
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.2.1.1 cytosol cytosolic isozymes hCA I and II Homo sapiens 5829
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
4.2.1.1 Zn2+ required Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.1 Homo sapiens
-
-
-

Synonyms

EC Number Synonyms Comment Organism
4.2.1.1 carbonic anhydrase I
-
 Homo sapiens
4.2.1.1 carbonic anhydrase II
-
 Homo sapiens