EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.1.64 | 2,2-dimethyl-4-phenyl-2H-imidazole-1-oxide | strong inhibition of isomerohydrolase activity (32% at 0.2 mM) in vitro | Bos taurus | |
3.1.1.64 | 2-(2-carboxyethyl)-2-methyl-4-phenyl-2H-imidazole-1-oxide | moderate inhibitory effect at 0.2 mM | Bos taurus | |
3.1.1.64 | additional information | not inhibited by N-tert-butyl-(2-sulfophenyl)nitrone, alpha-(4-pyridyl 1-oxide)-N-tert-butylnitrone, NXY059, tert-butylhydroxylamine, and 2-methyl-2-nitrosopropane | Bos taurus | |
3.1.1.64 | n-benzylidene-tert-butylamine | 14% inhibition at 0.2 mM | Bos taurus | |
3.1.1.64 | N-tert-butyl-alpha-phenylnitrone | strong uncompetitive inhibition (52%) of isomerohydrolase activity in vitro at 0.2 mM | Bos taurus | |
3.1.1.64 | nitrosobenzene | strong inhibition of isomerohydrolase activity in vitro at 0.2 mM | Bos taurus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.1.1.64 | microsome | - |
Bos taurus | - |
- |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.1.64 | Bos taurus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.1.64 | retinal pigment epithelial cell | - |
Bos taurus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.1.64 | all-trans-retinyl ester + H2O | - |
Bos taurus | 11-cis-retinol + a fatty acid | RPE65 does not specifically produce 11-cis-retinol only but also 13-cis-retinol | ? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.1.64 | Rpe65 | - |
Bos taurus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.1.64 | 0.061 | - |
N-tert-butyl-alpha-phenylnitrone | pH and temperature not specified in the publication | Bos taurus |