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Literature summary extracted from

  • Manna, D.; Mugesh, G.
    A chemical model for the inner-ring deiodination of thyroxine by iodothyronine deiodinase (2010), Angew. Chem., 49, 9246-9249.
No PubMed abstract available

Organism

EC Number Organism UniProt Comment Textmining
1.21.99.4 Homo sapiens
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-
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.21.99.4 3,3',5'-triiodo-L-thyronine + AH2 the reaction is catalyzed by the type 1 and 2 deiodinases Homo sapiens 3,3'-diiodo-L-thyronine + iodide + A + H+
-
?
1.21.99.4 L-thyroxine + AH2 the reaction is catalyzed by the type 1 and 2 deiodinases Homo sapiens 3,5,3'-triiodo-L-thyronine + iodide + A + H+
-
?

Synonyms

EC Number Synonyms Comment Organism
1.21.99.4 ID-1
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Homo sapiens
1.21.99.4 ID-2
-
Homo sapiens
1.21.99.4 ID-3
-
Homo sapiens
1.21.99.4 type 1 deiodinase
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Homo sapiens
1.21.99.4 type 2 deiodinase
-
Homo sapiens
1.21.99.4 type 3 deiodinase
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Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.21.99.4 dithioerythritol
-
Homo sapiens