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Literature summary extracted from
- The inhibitory effect of propofol on bovine lactoperoxidase (2009), Protein Pept. Lett., 16, 46-49.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.11.1.7 | propofol | i.e. 2,6-diisopropylphenol, competitive inhibitor | Bos taurus |  |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.11.1.7 | 0.000358 | - |
2,2'-azino-bis(3-ethylbenzthiazoline)-sulfonic acid | at 25°C, pH 6.0 | Bos taurus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.11.1.7 | Bos taurus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.11.1.7 | Amberlite CG-50 resin column chromatography, CM-Sephadex C-50 column chromatography, and Sephadex G-100 gel filtration | Bos taurus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.11.1.7 | milk | - |
Bos taurus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.11.1.7 | 2.3 | - |
crude enzyme, using 2,2'-azino-bis(3-ethylbenzthiazoline)-sulfonic acid as substrate, at 25°C, pH 6.0 | Bos taurus |
| 1.11.1.7 | 34 | - |
after 14.7fold purification, using 2,2'-azino-bis(3-ethylbenzthiazoline)-sulfonic acid as substrate, at 25°C, pH 6.0 | Bos taurus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.11.1.7 | 2,2'-azino-bis(3-ethylbenzthiazoline)-sulfonic acid + H2O2 | - |
Bos taurus | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.11.1.7 | lactoperoxidase | - |
Bos taurus |
| 1.11.1.7 | LPO | - |
Bos taurus |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.11.1.7 | heme | - |
Bos taurus | |
Ki Value [mM]
| EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.11.1.7 | 0.00372 | - |
propofol | at 25°C, pH 6.0 | Bos taurus | |
IC50 Value
| EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|---|
| 1.11.1.7 | 0.01597 | - |
at 25°C, pH 6.0 | Bos taurus | propofol | |
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Release 2023.1 (January 2023)
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