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Literature summary extracted from

  • Laketa, D.; Bjelobaba, I.; Savic, J.; Lavrnja, I.; Stojiljkovic, M.; Rakic, L.; Nedeljkovic, N.
    Biochemical characterization of soluble nucleotide pyrophosphatase/phosphodiesterase activity in rat serum (2010), Mol. Cell. Biochem., 339, 99-106.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.6.1.9 2',3'-dialdehyde ATP competitive inhibition Rattus norvegicus
3.6.1.9 2-methylthioadenosine 5'-triphosphate competitive inhibition Rattus norvegicus
3.6.1.9 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate competitive inhibition Rattus norvegicus
3.6.1.9 ADP competitive inhibition Rattus norvegicus
3.6.1.9 alpha,beta-methylene ADP mixed inhibition Rattus norvegicus
3.6.1.9 alpha,beta-methylene ATP competitive inhibition Rattus norvegicus
3.6.1.9 AMP competitive inhibition Rattus norvegicus
3.6.1.9 ATP competitive inhibition Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.6.1.9 0.0618
-
 4-nitrophenyl-5'-TMP pH and temperature not specified in the publication Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.6.1.9 soluble
-
 Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.9 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.6.1.9 serum
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.9 4-nitrophenyl-5'-TMP + H2O
-
 Rattus norvegicus 4-nitrophenol + 5'-TMP
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.6.1.9 NPP
-
 Rattus norvegicus
3.6.1.9 nucleotide pyrophosphatase/phosphodiesterase
-
 Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.6.1.9 10.5
-
-
 Rattus norvegicus

General Information

EC Number General Information Comment Organism
3.6.1.9 physiological function NPP activity is involved in generation, breakdown, and recycling of extracellular adenine nucleotides in the vascular compartment Rattus norvegicus