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Literature summary extracted from

  • Su, X.; Pradaux-Caggiano, F.; Thomas, M.P.; Szeto, M.W.; Halem, H.A.; Culler, M.D.; Vicker, N.; Potter, B.V.
    Discovery of adamantyl ethanone derivatives as potent 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) inhibitors (2010), ChemMedChem, 5, 1026-1044.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.146 expressed in HEK-293 cell Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.146 1-(2,4-dichlorophenyl)-2-(2-methylbenzo[d]thiazol-5-ylamino)-ethanone
-
 Homo sapiens
1.1.1.146 1-(4-chlorophenyl)-2-(2-methylbenzo[d]thiazol-5-ylamino)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(2,4-dichloro-benzylsulfanyl)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(2,4-dichloro-phenylmethanesulfonyl)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(2-chloro-benzylsulfanyl)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(2-chloro-phenylmethanesulfinyl)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(2-chloro-phenylmethanesulfonyl)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(2-methylbenzothiazol-5-ylamino)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(2-methylbenzothiazol-5-yloxy)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(3,4-dimethoxy-benzyloxy)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(3,4-dimethoxy-phenoxy)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(3-methylbenzylsulfanyl)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(3-trifluoromethyl-phenoxy)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(3-trifluoromethylbenzyloxy)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(4-chloro-benzenesulfinyl)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(4-chloro-benzenesulfonyl)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(4-chloro-benzyloxy)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(4-chloro-benzylsulfanyl)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(4-chloro-phenoxy)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(4-chloro-phenylmethanesulfinyl)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(4-chloro-phenylmethanesulfonyl)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(4-chloro-phenylsulfanyl)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(4-methoxy-benzyloxy)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(4-methylbenzyloxy)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(4-tert-butyl-phenylmethanesulfinyl)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(4-tert-butyl-phenylmethanesulfonyl)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(4-tert-butylbenzylsulfanyl)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(4-trifluoromethyl-phenoxy)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(4-trifluoromethylbenzyloxy)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(biphenyl-4-ylmethoxy)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(biphenyl-4-yloxy)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(toluene-4-sulfinyl)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-(toluene-4-sulfonyl)ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-m-tolylmethanesulfonyl-ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-p-tolyloxy-ethanone
-
 Homo sapiens
1.1.1.146 1-adamantan-1-yl-2-p-tolylsulfanyl-ethanone
-
 Homo sapiens
1.1.1.146 2-[4-(2-adamantan-1-yl-2-oxoethoxy)phenyl]-N,N-dimethyl-acetamide
-
 Homo sapiens
1.1.1.146 2-[4-(2-adamantan-1-yl-2-oxoethoxy)phenyl]-N-benzyl-acetamide
-
 Homo sapiens
1.1.1.146 2-[4-(2-adamantan-1-yl-2-oxoethoxy)phenyl]-N-ethyl-acetamide
-
 Homo sapiens
1.1.1.146 2-[4-(2-adamantan-1-yl-2-oxoethoxy)phenyl]-N-furan-2-ylmethyl-acetamide
-
 Homo sapiens
1.1.1.146 2-[4-(2-adamantan-1-yl-2-oxoethoxy)phenyl]-N-isopropyl-acetamide
-
 Homo sapiens
1.1.1.146 2-[4-(2-adamantan-1-yl-2-oxoethoxy)phenyl]-N-methyl-acetamide
-
 Homo sapiens
1.1.1.146 2-[4-(2-adamantan-1-yl-2-oxoethoxy)phenyl]-N-phenyl-acetamide
-
 Homo sapiens
1.1.1.146 2-[4-(2-adamantan-1-yl-2-oxoethoxy)phenyl]-N-tert-butyl-acetamide
-
 Homo sapiens
1.1.1.146 2-[4-(2-adamantan-1-yl-2-oxoethoxy)phenyl]acetamide
-
 Homo sapiens
1.1.1.146 3-(2-adamantan-1-yl-2-oxoethanesulfinyl)-N,N-dimethylbenzamide
-
 Homo sapiens
1.1.1.146 3-(2-adamantan-1-yl-2-oxoethanesulfonyl)-N,N-dimethylbenzamide
-
 Homo sapiens
1.1.1.146 3-(2-adamantan-1-yl-2-oxoethoxy)-N-benzylbenzamide
-
 Homo sapiens
1.1.1.146 3-(2-adamantan-1-yl-2-oxoethoxy)-N-ethylbenzamide
-
 Homo sapiens
1.1.1.146 3-(2-adamantan-1-yl-2-oxoethoxy)-N-furan-2-ylmethylbenzamide
-
 Homo sapiens
1.1.1.146 3-(2-adamantan-1-yl-2-oxoethoxy)-N-isopropylbenzamide
-
 Homo sapiens
1.1.1.146 3-(2-adamantan-1-yl-2-oxoethoxy)-N-methylbenzamide
-
 Homo sapiens
1.1.1.146 3-(2-adamantan-1-yl-2-oxoethoxy)-N-phenylbenzamide
-
 Homo sapiens
1.1.1.146 3-(2-adamantan-1-yl-2-oxoethoxy)-N-tert-butylbenzamide
-
 Homo sapiens
1.1.1.146 3-(2-adamantan-1-yl-2-oxoethoxy)benzamide
-
 Homo sapiens
1.1.1.146 3-(2-adamantan-1-yl-2-oxoethoxy)benzoic acid
-
 Homo sapiens
1.1.1.146 3-(2-adamantan-1-yl-2-oxoethoxy)benzoic acid methyl ester
-
 Homo sapiens
1.1.1.146 3-[[2-(adamantan-1-yl)-2-oxoethyl]sulfanyl]-N,N-dimethyl benzamide
-
 Homo sapiens
1.1.1.146 3-[[2-(adamantan-1-yl)-2-oxoethyl]sulfanyl]-N-methylbenzamide
-
 Homo sapiens
1.1.1.146 4-(2-adamantan-1-yl-2-oxoethoxy)-N,N-diethylbenzamide
-
 Homo sapiens
1.1.1.146 4-(2-adamantan-1-yl-2-oxoethoxy)-N-benzylbenzamide
-
 Homo sapiens
1.1.1.146 4-(2-adamantan-1-yl-2-oxoethoxy)-N-ethylbenzamide
-
 Homo sapiens
1.1.1.146 4-(2-adamantan-1-yl-2-oxoethoxy)-N-furan-2-ylmethylbenzamide
-
 Homo sapiens
1.1.1.146 4-(2-adamantan-1-yl-2-oxoethoxy)-N-isopropylbenzamide
-
 Homo sapiens
1.1.1.146 4-(2-adamantan-1-yl-2-oxoethoxy)-N-methylbenzamide
-
 Homo sapiens
1.1.1.146 4-(2-adamantan-1-yl-2-oxoethoxy)-N-phenylbenzamide
-
 Homo sapiens
1.1.1.146 4-(2-adamantan-1-yl-2-oxoethoxy)-N-tert-butylbenzamide
-
 Homo sapiens
1.1.1.146 4-(2-adamantan-1-yl-2-oxoethoxy)benzamide
-
 Homo sapiens
1.1.1.146 4-(2-adamantan-1-yl-2-oxoethoxy)benzoic acid
-
 Homo sapiens
1.1.1.146 4-(2-adamantan-1-yl-2-oxoethoxy)benzoic acid methyl ester
-
 Homo sapiens
1.1.1.146 4-(2-adamantan-1-yl-2-oxoethoxymethyl)-N,N-dimethylbenzamide
-
 Homo sapiens
1.1.1.146 4-(2-adamantan-1-yl-2-oxoethoxymethyl)-N-benzylbenzamide
-
 Homo sapiens
1.1.1.146 4-(2-adamantan-1-yl-2-oxoethoxymethyl)-N-methylbenzamide
-
 Homo sapiens
1.1.1.146 4-(2-adamantan-1-yl-2-oxoethoxymethyl)benzamide
-
 Homo sapiens
1.1.1.146 4-(2-adamantan-1-yl-2-oxoethoxymethyl)benzoic acid
-
 Homo sapiens
1.1.1.146 4-(2-adamantan-1-yl-2-oxoethoxymethyl)benzoic acid methyl ester
-
 Homo sapiens
1.1.1.146 N-[3-(2-adamantan-1-yl-2-oxoethanesulfinyl)phenyl]acetamide
-
 Homo sapiens
1.1.1.146 N-[3-(2-adamantan-1-yl-2-oxoethanesulfonyl)phenyl]acetamide
-
 Homo sapiens
1.1.1.146 N-[3-(2-adamantan-1-yl-2-oxoethoxy)phenyl]acetamide
-
 Homo sapiens
1.1.1.146 N-[3-(2-adamantan-1-yl-2-oxoethylsulfanyl)phenyl]acetamide
-
 Homo sapiens
1.1.1.146 N-[4-(2-adamantan-1-yl-2-oxoethanesulfinyl)phenyl]acetamide
-
 Homo sapiens
1.1.1.146 N-[4-(2-adamantan-1-yl-2-oxoethanesulfonyl)phenyl]acetamide
-
 Homo sapiens
1.1.1.146 N-[4-(2-adamantan-1-yl-2-oxoethoxy)-2-chloro-phenyl]acetamide
-
 Homo sapiens
1.1.1.146 N-[4-(2-adamantan-1-yl-2-oxoethoxy)-2-fluoro-phenyl]acetamide
-
 Homo sapiens
1.1.1.146 N-[4-(2-adamantan-1-yl-2-oxoethoxy)-2-methyl-phenyl]acetamide
-
 Homo sapiens
1.1.1.146 N-[4-(2-adamantan-1-yl-2-oxoethoxy)-3-chloro-phenyl]acetamide
-
 Homo sapiens
1.1.1.146 N-[4-(2-adamantan-1-yl-2-oxoethoxy)-3-methyl-phenyl]acetamide
-
 Homo sapiens
1.1.1.146 N-[4-(2-adamantan-1-yl-2-oxoethoxy)phenyl]acetamide
-
 Homo sapiens
1.1.1.146 N-[4-(2-adamantan-1-yl-2-oxoethylamino)phenyl]acetamide
-
 Homo sapiens
1.1.1.146 N-[4-(2-adamantan-1-yl-2-oxoethylsulfanyl)phenyl]acetamide
-
 Homo sapiens
1.1.1.146 [4-(2-adamantan-1-yl-2-oxoethoxy)phenyl]acetic acid
-
 Homo sapiens
1.1.1.146 [4-(2-Adamantan-1-yl-2-oxoethoxy)phenyl]acetic acid methyl ester
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.146 Homo sapiens P28845
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.146 adipose tissue
-
 Homo sapiens
-
1.1.1.146 liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.146 cortisone + NADPH + H+
-
 Homo sapiens cortisol + NADP+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.146 11beta-hydroxysteroid dehydrogenase type 1
-
 Homo sapiens

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
1.1.1.146 additional information
-
 24% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(2-chloro-benzylsulfanyl)ethanone
1.1.1.146 additional information
-
 25% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens 4-(2-adamantan-1-yl-2-oxoethoxy)benzoic acid methyl ester
1.1.1.146 additional information
-
 26% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(3-methylbenzylsulfanyl)ethanone
1.1.1.146 additional information
-
 31% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(3-trifluoromethylbenzyloxy)ethanone
1.1.1.146 additional information
-
 35% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(4-trifluoromethylbenzyloxy)ethanone
1.1.1.146 additional information
-
 38% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(biphenyl-4-ylmethoxy)ethanone
1.1.1.146 additional information
-
 4% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens 2-[4-(2-adamantan-1-yl-2-oxoethoxy)phenyl]-N-furan-2-ylmethyl-acetamide
1.1.1.146 additional information
-
 45% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens 2-[4-(2-adamantan-1-yl-2-oxoethoxy)phenyl]-N-tert-butyl-acetamide
1.1.1.146 additional information
-
 45% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-m-tolylmethanesulfonyl-ethanone
1.1.1.146 additional information
-
 46% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(3-trifluoromethyl-phenoxy)ethanone
1.1.1.146 additional information
-
 49% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens N-[4-(2-adamantan-1-yl-2-oxoethoxy)-2-chloro-phenyl]acetamide
1.1.1.146 additional information
-
 53% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(4-chloro-benzyloxy)ethanone
1.1.1.146 additional information
-
 55% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens 4-(2-adamantan-1-yl-2-oxoethoxymethyl)benzoic acid methyl ester
1.1.1.146 additional information
-
 56% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(4-chloro-benzenesulfonyl)ethanone
1.1.1.146 additional information
-
 59% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens 3-(2-adamantan-1-yl-2-oxoethoxy)-N-tert-butylbenzamide
1.1.1.146 additional information
-
 60% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(4-tert-butyl-phenylmethanesulfinyl)ethanone
1.1.1.146 additional information
-
 61% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens N-[4-(2-adamantan-1-yl-2-oxoethoxy)-3-chloro-phenyl]acetamide
1.1.1.146 additional information
-
 63% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens 4-(2-adamantan-1-yl-2-oxoethoxy)-N-methylbenzamide
1.1.1.146 additional information
-
 63% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens 2-[4-(2-adamantan-1-yl-2-oxoethoxy)phenyl]-N-isopropyl-acetamide
1.1.1.146 additional information
-
 63% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens 4-(2-adamantan-1-yl-2-oxoethoxymethyl)benzamide
1.1.1.146 additional information
-
 68% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(2,4-dichloro-benzylsulfanyl)ethanone
1.1.1.146 additional information
-
 68% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens N-[4-(2-adamantan-1-yl-2-oxoethoxy)-2-methyl-phenyl]acetamide
1.1.1.146 additional information
-
 68% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(4-tert-butylbenzylsulfanyl)ethanone
1.1.1.146 additional information
-
 69% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens 4-(2-adamantan-1-yl-2-oxoethoxy)-N-furan-2-ylmethylbenzamide
1.1.1.146 additional information
-
 69% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens 4-(2-adamantan-1-yl-2-oxoethoxymethyl)-N-benzylbenzamide
1.1.1.146 additional information
-
 74% inhibition at 0.001 mM, pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(4-chloro-benzylsulfanyl)ethanone
1.1.1.146 0.000056
-
 pH not specified in the publication, 37°C Homo sapiens 4-(2-adamantan-1-yl-2-oxoethoxymethyl)-N,N-dimethylbenzamide
1.1.1.146 0.000057
-
 pH not specified in the publication, 37°C Homo sapiens 3-(2-adamantan-1-yl-2-oxoethanesulfinyl)-N,N-dimethylbenzamide
1.1.1.146 0.000058
-
 pH not specified in the publication, 37°C Homo sapiens N-[4-(2-adamantan-1-yl-2-oxoethanesulfonyl)phenyl]acetamide
1.1.1.146 0.000058
-
 pH not specified in the publication, 37°C Homo sapiens 2-[4-(2-adamantan-1-yl-2-oxoethoxy)phenyl]-N,N-dimethyl-acetamide
1.1.1.146 0.000068
-
 pH not specified in the publication, 37°C Homo sapiens 3-(2-adamantan-1-yl-2-oxoethoxy)-N-methylbenzamide
1.1.1.146 0.000069
-
 pH not specified in the publication, 37°C Homo sapiens 3-(2-adamantan-1-yl-2-oxoethanesulfonyl)-N,N-dimethylbenzamide
1.1.1.146 0.000074
-
 pH not specified in the publication, 37°C Homo sapiens 4-(2-adamantan-1-yl-2-oxoethoxy)benzoic acid
1.1.1.146 0.000078
-
 pH not specified in the publication, 37°C Homo sapiens 3-(2-adamantan-1-yl-2-oxoethoxy)benzoic acid methyl ester
1.1.1.146 0.00009
-
 pH not specified in the publication, 37°C Homo sapiens N-[4-(2-adamantan-1-yl-2-oxoethylamino)phenyl]acetamide
1.1.1.146 0.000094
-
 pH not specified in the publication, 37°C Homo sapiens 2-[4-(2-adamantan-1-yl-2-oxoethoxy)phenyl]-N-methyl-acetamide
1.1.1.146 0.000105
-
 pH not specified in the publication, 37°C Homo sapiens N-[3-(2-adamantan-1-yl-2-oxoethanesulfinyl)phenyl]acetamide
1.1.1.146 0.000117
-
 pH not specified in the publication, 37°C Homo sapiens 4-(2-adamantan-1-yl-2-oxoethoxy)benzamide
1.1.1.146 0.000122
-
 pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(2-chloro-phenylmethanesulfinyl)ethanone
1.1.1.146 0.000124
-
 pH not specified in the publication, 37°C Homo sapiens 3-[[2-(adamantan-1-yl)-2-oxoethyl]sulfanyl]-N-methylbenzamide
1.1.1.146 0.000128
-
 pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(2-chloro-phenylmethanesulfonyl)ethanone
1.1.1.146 0.000146
-
 pH not specified in the publication, 37°C Homo sapiens 3-[[2-(adamantan-1-yl)-2-oxoethyl]sulfanyl]-N,N-dimethyl benzamide
1.1.1.146 0.000151
-
 pH not specified in the publication, 37°C Homo sapiens N-[4-(2-adamantan-1-yl-2-oxoethanesulfinyl)phenyl]acetamide
1.1.1.146 0.000153
-
 pH not specified in the publication, 37°C Homo sapiens 3-(2-adamantan-1-yl-2-oxoethoxy)benzoic acid
1.1.1.146 0.000167
-
 pH not specified in the publication, 37°C Homo sapiens N-[3-(2-adamantan-1-yl-2-oxoethanesulfonyl)phenyl]acetamide
1.1.1.146 0.000171
-
 pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(2,4-dichloro-phenylmethanesulfonyl)ethanone
1.1.1.146 0.000204
-
 pH not specified in the publication, 37°C Homo sapiens 2-[4-(2-adamantan-1-yl-2-oxoethoxy)phenyl]acetamide
1.1.1.146 0.000211
-
 pH not specified in the publication, 37°C Homo sapiens N-[4-(2-adamantan-1-yl-2-oxoethoxy)phenyl]acetamide
1.1.1.146 0.000229
-
 pH not specified in the publication, 37°C Homo sapiens 3-(2-adamantan-1-yl-2-oxoethoxy)-N-furan-2-ylmethylbenzamide
1.1.1.146 0.000231
-
 pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(4-chloro-phenylmethanesulfinyl)ethanone
1.1.1.146 0.00025
-
 pH not specified in the publication, 37°C Homo sapiens 4-(2-adamantan-1-yl-2-oxoethoxymethyl)-N-methylbenzamide
1.1.1.146 0.000283
-
 pH not specified in the publication, 37°C Homo sapiens 4-(2-adamantan-1-yl-2-oxoethoxy)-N-phenylbenzamide
1.1.1.146 0.000285
-
 pH not specified in the publication, 37°C Homo sapiens N-[3-(2-adamantan-1-yl-2-oxoethoxy)phenyl]acetamide
1.1.1.146 0.000296
-
 pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(4-methoxy-benzyloxy)ethanone
1.1.1.146 0.000302
-
 pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(2-methylbenzothiazol-5-ylamino)ethanone
1.1.1.146 0.000313
-
 pH not specified in the publication, 37°C Homo sapiens N-[4-(2-adamantan-1-yl-2-oxoethylsulfanyl)phenyl]acetamide
1.1.1.146 0.000339
-
 pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(3,4-dimethoxy-benzyloxy)ethanone
1.1.1.146 0.000343
-
 pH not specified in the publication, 37°C Homo sapiens 3-(2-adamantan-1-yl-2-oxoethoxy)-N-ethylbenzamide
1.1.1.146 0.000359
-
 pH not specified in the publication, 37°C Homo sapiens 4-(2-adamantan-1-yl-2-oxoethoxymethyl)benzoic acid
1.1.1.146 0.000382
-
 pH not specified in the publication, 37°C Homo sapiens 4-(2-adamantan-1-yl-2-oxoethoxy)-N-ethylbenzamide
1.1.1.146 0.0004
-
 pH not specified in the publication, 37°C Homo sapiens [4-(2-adamantan-1-yl-2-oxoethoxy)phenyl]acetic acid
1.1.1.146 0.000443
-
 pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(toluene-4-sulfinyl)ethanone
1.1.1.146 0.000472
-
 pH not specified in the publication, 37°C Homo sapiens 2-[4-(2-adamantan-1-yl-2-oxoethoxy)phenyl]-N-benzyl-acetamide
1.1.1.146 0.000527
-
 pH not specified in the publication, 37°C Homo sapiens 3-(2-adamantan-1-yl-2-oxoethoxy)-N-benzylbenzamide
1.1.1.146 0.000594
-
 pH not specified in the publication, 37°C Homo sapiens 4-(2-adamantan-1-yl-2-oxoethoxy)-N-isopropylbenzamide
1.1.1.146 0.000668
-
 pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(toluene-4-sulfonyl)ethanone
1.1.1.146 0.000798
-
 pH not specified in the publication, 37°C Homo sapiens 4-(2-adamantan-1-yl-2-oxoethoxy)-N,N-diethylbenzamide
1.1.1.146 0.00081
-
 pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(4-chloro-phenylsulfanyl)ethanone
1.1.1.146 0.000876
-
 pH not specified in the publication, 37°C Homo sapiens 3-(2-adamantan-1-yl-2-oxoethoxy)-N-phenylbenzamide
1.1.1.146 0.000894
-
 pH not specified in the publication, 37°C Homo sapiens N-[4-(2-adamantan-1-yl-2-oxoethoxy)-2-fluoro-phenyl]acetamide
1.1.1.146 0.000897
-
 pH not specified in the publication, 37°C Homo sapiens N-[4-(2-adamantan-1-yl-2-oxoethoxy)-3-methyl-phenyl]acetamide
1.1.1.146 0.000912
-
 pH not specified in the publication, 37°C Homo sapiens 2-[4-(2-adamantan-1-yl-2-oxoethoxy)phenyl]-N-ethyl-acetamide
1.1.1.146 0.001
-
 pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(4-chloro-phenoxy)ethanone
1.1.1.146 0.001047
-
 pH not specified in the publication, 37°C Homo sapiens 3-(2-adamantan-1-yl-2-oxoethoxy)benzamide
1.1.1.146 0.00114
-
 pH not specified in the publication, 37°C Homo sapiens 4-(2-adamantan-1-yl-2-oxoethoxy)-N-tert-butylbenzamide
1.1.1.146 0.001222
-
 pH not specified in the publication, 37°C Homo sapiens 3-(2-adamantan-1-yl-2-oxoethoxy)-N-isopropylbenzamide
1.1.1.146 0.00135
-
 pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(4-chloro-phenylmethanesulfonyl)ethanone
1.1.1.146 0.001438
-
 pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(4-chloro-benzenesulfinyl)ethanone
1.1.1.146 0.001959
-
 pH not specified in the publication, 37°C Homo sapiens 4-(2-adamantan-1-yl-2-oxoethoxy)-N-benzylbenzamide
1.1.1.146 0.002017
-
 pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(4-tert-butyl-phenylmethanesulfonyl)ethanone
1.1.1.146 0.002037
-
 pH not specified in the publication, 37°C Homo sapiens N-[3-(2-adamantan-1-yl-2-oxoethylsulfanyl)phenyl]acetamide
1.1.1.146 0.002069
-
 pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(4-methylbenzyloxy)ethanone
1.1.1.146 0.002194
-
 pH not specified in the publication, 37°C Homo sapiens 2-[4-(2-adamantan-1-yl-2-oxoethoxy)phenyl]-N-phenyl-acetamide
1.1.1.146 0.00251
-
 pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-p-tolyloxy-ethanone
1.1.1.146 0.00258
-
 pH not specified in the publication, 37°C Homo sapiens [4-(2-Adamantan-1-yl-2-oxoethoxy)phenyl]acetic acid methyl ester
1.1.1.146 0.002975
-
 pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(2,4-dichloro-benzylsulfanyl)ethanone
1.1.1.146 0.004755
-
 pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(2-methylbenzothiazol-5-yloxy)ethanone
1.1.1.146 0.0049
-
 pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(biphenyl-4-yloxy)ethanone
1.1.1.146 0.005236
-
 pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(4-trifluoromethyl-phenoxy)ethanone
1.1.1.146 0.0058
-
 pH not specified in the publication, 37°C Homo sapiens 1-(2,4-dichlorophenyl)-2-(2-methylbenzo[d]thiazol-5-ylamino)-ethanone
1.1.1.146 0.0064
-
 pH not specified in the publication, 37°C Homo sapiens 1-(4-chlorophenyl)-2-(2-methylbenzo[d]thiazol-5-ylamino)ethanone
1.1.1.146 0.00672
-
 pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-p-tolylsulfanyl-ethanone
1.1.1.146 0.009379
-
 pH not specified in the publication, 37°C Homo sapiens 1-adamantan-1-yl-2-(3,4-dimethoxy-phenoxy)ethanone