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Literature summary extracted from

  • Nam, E.; Lee, C.
    Contribution of the porcine aminopeptidase N (CD13) receptor density to porcine epidemic diarrhea virus infection (2010), Vet. Microbiol., 144, 41-50.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.11.2 expressed in Escherichia coli DH5alpha and HEK-293T cells cells Sus scrofa

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.2 1,10-phenanthroline
-
 Sus scrofa
3.4.11.2 2,2'-dipyridyl
-
 Sus scrofa
3.4.11.2 bestatin
-
 Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.11.2 plasma membrane
-
 Sus scrofa 5886
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.11.2 Zn2+ zinc-dependent metalloprotease Sus scrofa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.11.2 150000
-
 gel filtration Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.2 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.11.2 testis
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.2 L-Leu-4-nitroanilide + H2O
-
 Sus scrofa L-Leu + 4-nitroaniline
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.11.2 aminopeptidase N
-
 Sus scrofa
3.4.11.2 APN
-
 Sus scrofa
3.4.11.2 CD13
-
 Sus scrofa

General Information

EC Number General Information Comment Organism
3.4.11.2 physiological function porcine epidemic diarrhea virus and transmissible gastroenteritis virus use the host aminopeptidase N as the major receptor for cell entry, APN receptor density is an important factor in contributing to efficient porcine epidemic diarrhea virus infection Sus scrofa