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Literature summary extracted from
- Highlights and hotspots of protein glycation in end-stage renal disease (2009), Semin. Dial., 22, 400-404.
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.4.1.5 | methylglyoxal + glutathione | Homo sapiens | - |
(R)-S-lactoylglutathione | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.4.1.5 | Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.4.1.5 | methylglyoxal + glutathione | - |
Homo sapiens | (R)-S-lactoylglutathione | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 4.4.1.5 | glyoxalase I | - |
Homo sapiens |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.4.1.5 | glutathione | - |
Homo sapiens | |
Expression
| EC Number | Organism | Comment | Expression |
|---|---|---|---|
| 4.4.1.5 | Homo sapiens | activation of receptor for advanced glycation endproducts by S100A12 protein decreases the expression of glyoxalase 1 | down |
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Release 2023.1 (January 2023)
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