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Literature summary extracted from
- Glyoxalase I gene deletion mutants of Leishmania donovani exhibit reduced methylglyoxal detoxification (2009), PLoS ONE, 4, e6805.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 4.4.1.5 | kinetoplast | - |
Leishmania donovani | 20023 | - |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 4.4.1.5 | 16000 | - |
native enzyme, SDS-PAGE | Leishmania donovani |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.4.1.5 | Leishmania donovani | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 4.4.1.5 | promastigote | - |
Leishmania donovani | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.4.1.5 | methylglyoxal + glutathione | - |
Leishmania donovani | (R)-S-lactoylglutathione | - |
? |  |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 4.4.1.5 | GloI | - |
Leishmania donovani |
| 4.4.1.5 | glyoxalase I | - |
Leishmania donovani |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.4.1.5 | glutathione | - |
Leishmania donovani | |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 4.4.1.5 | malfunction | GLO I heterozygous mutants exhibit reduced methylglyoxal detoxification | Leishmania donovani |
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Release 2023.1 (January 2023)
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