Literature summary extracted from

Henneke, M.; Dreha-Kulaczewski, S.; Brockmann, K.; van der Graaf, M.; Willemsen, M.A.; Engelke, U.; Dechent, P.; Heerschap, A.; Helms, G.; Wevers, R.A.; Gaertner, J.
In vivo proton MR spectroscopy findings specific for adenylosuccinate lyase deficiency (2010), NMR Biomed., 23, 441-445.

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
4.3.2.2	5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide	Homo sapiens	-	5-aminoimidazole-4-carboxamide ribonucleotide + fumarate	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.3.2.2	Homo sapiens	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.3.2.2	5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide	-	Homo sapiens	5-aminoimidazole-4-carboxamide ribonucleotide + fumarate	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
4.3.2.2	ADSL	-	Homo sapiens

General Information

EC Number	General Information	Comment	Organism
4.3.2.2	malfunction	adenylosuccinate lyase deficiency is characterized by the accumulation of 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide and succinyladenosine in tissue and body fluids	Homo sapiens

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Release 2023.1 (January 2023)