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Literature summary extracted from
- Nitric oxide and carbon monoxide act as inhibitory neurotransmitters in the longitudinal muscle of C57BL/6J mouse distal colon (2010), J. Pharmacol. Sci., 112, 231-241.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.6.1.2 | carbon monoxide | - |
Mus musculus |  |
| 4.6.1.2 | nitric oxide | - |
Mus musculus | |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.6.1.2 | 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one | a soluble guanylate cyclase inhibitor, maximal inhibition (70%) at 0.01 mM | Mus musculus | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.6.1.2 | GTP | Mus musculus | - |
3',5'-cyclic-GMP + diphosphate | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.6.1.2 | Mus musculus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 4.6.1.2 | gastrointestinal smooth muscle | - |
Mus musculus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.6.1.2 | GTP | - |
Mus musculus | 3',5'-cyclic-GMP + diphosphate | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 4.6.1.2 | sGC | - |
Mus musculus |
| 4.6.1.2 | soluble guanylyl cyclase | - |
Mus musculus |
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Release 2023.1 (January 2023)
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