Literature summary extracted from

Kwak, Y.K.; Hoegbom, M.; Colque-Navarro, P.; Moellby, R.; Vecsey-Semjen, B.
Biological relevance of natural alpha-toxin fragments from Staphylococcus aureus (2010), J. Membr. Biol., 233, 93-103.

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
3.4.21.19	extracellular	the enzyme is secreted	Staphylococcus aureus	-	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.21.19	Staphylococcus aureus	-	-	-
3.4.21.19	Staphylococcus aureus Wood 46	-	-	-
3.4.24.29	Staphylococcus aureus	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.4.21.19	pore-forming alpha-toxin + H2O	limited proteolysis with V8 protease	Staphylococcus aureus	pore-forming alpha-toxin peptide fragments	product identification, eight or more fragments are produced by V8 treatment, cleavage pattern, overview	?
3.4.21.19	pore-forming alpha-toxin + H2O	limited proteolysis with V8 protease	Staphylococcus aureus Wood 46	pore-forming alpha-toxin peptide fragments	product identification, eight or more fragments are produced by V8 treatment, cleavage pattern, overview	?
3.4.24.29	alpha-toxin + H2O	-	Staphylococcus aureus	?	-	?
3.4.24.29	alpha-toxin + H2O	-	Staphylococcus aureus Wood 46	?	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
3.4.21.19	V8 protease	-	Staphylococcus aureus

Temperature Optimum [°C]

EC Number	Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
3.4.21.19	37	-	assay at	Staphylococcus aureus

pH Optimum

EC Number	pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
3.4.21.19	7.4	-	assay at	Staphylococcus aureus

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Release 2023.1 (January 2023)