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Literature summary extracted from

  • Baig, M.S.; Kumar, A.; Siddiqi, M.I.; Goyal, N.
    Characterization of dipeptidylcarboxypeptidase of Leishmania donovani: a molecular model for structure based design of antileishmanials (2010), J. Comput. Aided Mol. Des., 24, 77-87.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.15.1 expression in Escherichia coli strain BL21(DE3) Leishmania donovani

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.15.1 bradykinin potentiating peptide i.e. BPP1 or pGlu-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro Leishmania donovani
3.4.15.1 captopril binding mode, molecular docking, detailed overview Leishmania donovani

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.15.1 4
-
 hippuryl-His-Leu
-
 Leishmania donovani

Organism

EC Number Organism UniProt Comment Textmining
3.4.15.1 Leishmania donovani Q4KXL2
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.15.1 recombinant enzyme from Escherichia coli strain BL21(DE3) to homogeneity Leishmania donovani

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.15.1 hippuryl-His-Leu + H2O
-
 Leishmania donovani hippuric acid + His-Leu
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.15.1 More enzyme homology modelling, overview Leishmania donovani

Synonyms

EC Number Synonyms Comment Organism
3.4.15.1 ACE
-
 Leishmania donovani
3.4.15.1 DCP
-
 Leishmania donovani
3.4.15.1 dipeptidylcarboxypeptidase
-
 Leishmania donovani