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Literature summary extracted from

  • Ng, S.Y.; VanDyke, D.J.; Chaban, B.; Wu, J.; Nosaka, Y.; Aizawa, S.; Jarrell, K.F.
    Different minimal signal peptide lengths recognized by the archaeal prepilin-like peptidases FlaK and PibD (2009), J. Bacteriol., 191, 6732-6740.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.23.52 a His-tagged version expressed in Escherichia coli Saccharolobus solfataricus
3.4.23.52 expressed in an Methanococcus maripaludis DELTAflaK strain Methanococcus maripaludis
3.4.23.52 expressed in an Methanococcus maripaludis DELTAflaK strain and in Escherichia coli Saccharolobus solfataricus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.23.52 FlaB2 protein + H2O Methanococcus voltae
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.23.52 Methanococcus maripaludis
-
-
-
3.4.23.52 Methanococcus voltae
-
-
-
3.4.23.52 Saccharolobus solfataricus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.23.52 crude membrane fraction Saccharolobus solfataricus
3.4.23.52 crude membrane fraction Methanococcus maripaludis
3.4.23.52 crude membrane fraction Methanococcus voltae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.23.52 FlaB2 protein + H2O
-
 Methanococcus voltae ?
-
 ?
3.4.23.52 FlaB2 protein + H2O FlaB2 protein of Methanococcus voltae Saccharolobus solfataricus ?
-
 ?
3.4.23.52 FlaB2 protein + H2O FlaB2 protein of Methanococcus voltae Methanococcus maripaludis ?
-
 ?
3.4.23.52 MEFMSNKKGASGIGTLIVFIAMVLVAAV + H2O
-
 Saccharolobus solfataricus MEFMSNKKG + ASGIGTLIVFIAMVLVAAV
-
 ?
3.4.23.52 MEFMSNKKGASGIGTLIVFIAMVLVAAV + H2O
-
 Methanococcus maripaludis MEFMSNKKG + ASGIGTLIVFIAMVLVAAV
-
 ?
3.4.23.52 MEFMSNKKGASGIGTLIVFIAMVLVAAV + H2O
-
 Methanococcus voltae MEFMSNKKG + ASGIGTLIVFIAMVLVAAV
-
 ?
3.4.23.52 MFMSNKKGASGIGTLIVFIAMVLVAAV + H2O
-
 Saccharolobus solfataricus MFMSNKKG + ASGIGTLIVFIAMVLVAAV
-
 ?
3.4.23.52 MFMSNKKGASGIGTLIVFIAMVLVAAV + H2O
-
 Methanococcus maripaludis MFMSNKKG + ASGIGTLIVFIAMVLVAAV
-
 ?
3.4.23.52 MFMSNKKGASGIGTLIVFIAMVLVAAV + H2O
-
 Methanococcus voltae MFMSNKKG + ASGIGTLIVFIAMVLVAAV
-
 ?
3.4.23.52 MKEFMSNKKGASGIGTLIVFIAMVLVAAV + H2O
-
 Saccharolobus solfataricus MKEFMSNKKG + ASGIGTLIVFIAMVLVAAV
-
 ?
3.4.23.52 MKEFMSNKKGASGIGTLIVFIAMVLVAAV + H2O
-
 Methanococcus maripaludis MKEFMSNKKG + ASGIGTLIVFIAMVLVAAV
-
 ?
3.4.23.52 MKEFMSNKKGASGIGTLIVFIAMVLVAAV + H2O
-
 Methanococcus voltae MKEFMSNKKG + ASGIGTLIVFIAMVLVAAV
-
 ?
3.4.23.52 MKGASGIGTLIVFIAMVLVAAV + H2O
-
 Saccharolobus solfataricus MKG + ASGIGTLIVFIAMVLVAAV
-
 ?
3.4.23.52 MKKGASGIGTLIVFIAMVLVAAV + H2O
-
 Saccharolobus solfataricus MKKG + ASGIGTLIVFIAMVLVAAV
-
 ?
3.4.23.52 MMSNKKGASGIGTLIVFIAMVLVAAV + H2O
-
 Saccharolobus solfataricus MMSNKKG + ASGIGTLIVFIAMVLVAAV
-
 ?
3.4.23.52 MMSNKKGASGIGTLIVFIAMVLVAAV + H2O
-
 Methanococcus maripaludis MMSNKKG + ASGIGTLIVFIAMVLVAAV
-
 ?
3.4.23.52 MMSNKKGASGIGTLIVFIAMVLVAAV + H2O
-
 Methanococcus voltae MMSNKKG + ASGIGTLIVFIAMVLVAAV
-
 ?
3.4.23.52 MNKKGASGIGTLIVFIAMVLVAAV + H2O
-
 Saccharolobus solfataricus MNKKG + ASGIGTLIVFIAMVLVAAV
-
 ?
3.4.23.52 MNKKGASGIGTLIVFIAMVLVAAV + H2O
-
 Methanococcus maripaludis MNKKG + ASGIGTLIVFIAMVLVAAV
-
 ?
3.4.23.52 MNKKGASGIGTLIVFIAMVLVAAV + H2O
-
 Methanococcus voltae MNKKG + ASGIGTLIVFIAMVLVAAV
-
 ?
3.4.23.52 additional information FlaK processes preflagellins with a minimum signal peptide length of 5 amino acids Methanococcus maripaludis ?
-
 ?
3.4.23.52 additional information FlaK processes preflagellins with a minimum signal peptide length of 5 amino acids Methanococcus voltae ?
-
 ?
3.4.23.52 additional information no activity with MKKGASGIGTLIVFIAMVLVAAV and MKGASGIGTLIVFIAMVLVAAV Methanococcus maripaludis ?
-
 ?
3.4.23.52 additional information no activity with MKKGASGIGTLIVFIAMVLVAAV and MKGASGIGTLIVFIAMVLVAAV Methanococcus voltae ?
-
 ?
3.4.23.52 MSNKKGASGIGTLIVFIAMVLVAAV + H2O
-
 Saccharolobus solfataricus MSNKKG + ASGIGTLIVFIAMVLVAAV
-
 ?
3.4.23.52 MSNKKGASGIGTLIVFIAMVLVAAV + H2O
-
 Methanococcus maripaludis MSNKKG + ASGIGTLIVFIAMVLVAAV
-
 ?
3.4.23.52 MSNKKGASGIGTLIVFIAMVLVAAV + H2O
-
 Methanococcus voltae MSNKKG + ASGIGTLIVFIAMVLVAAV
-
 ?
3.4.23.52 preflagellin FlaB2 + H2O preflagellin is MKIKEFMSNKKGASGIGTLIVFIAMVLVAAV Saccharolobus solfataricus MKIKEFMSNKKG + flagellin
-
 ?
3.4.23.52 preflagellin FlaB2 + H2O preflagellin is MKIKEFMSNKKGASGIGTLIVFIAMVLVAAV, the enzyme cleaves the 12 amino acid N-terminal signal peptide from preflagellinFlaB2 between Gly and L-Ala Methanococcus maripaludis MKIKEFMSNKKG + flagellin
-
 ?
3.4.23.52 preflagellin FlaB2 + H2O preflagellin is MKIKEFMSNKKGASGIGTLIVFIAMVLVAAV, the enzyme cleaves the 12 amino acid N-terminal signal peptide from preflagellinFlaB2 between Gly and L-Ala Methanococcus voltae MKIKEFMSNKKG + flagellin
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.23.52 FlaK
-
 Methanococcus maripaludis
3.4.23.52 FlaK
-
 Methanococcus voltae
3.4.23.52 PibD
-
 Saccharolobus solfataricus
3.4.23.52 preflagellin peptidase
-
 Saccharolobus solfataricus
3.4.23.52 preflagellin peptidase
-
 Methanococcus maripaludis
3.4.23.52 preflagellin peptidase
-
 Methanococcus voltae
3.4.23.52 prepilin-like peptidase
-
 Methanococcus maripaludis
3.4.23.52 prepilin-like peptidase
-
 Methanococcus voltae