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Literature summary extracted from
- N-Acylphosphatidylethanolamine-hydrolysing phospholipase D lacks the ability to transphosphatidylate (1999), FEBS Lett., 455, 41-44.
General Stability
| EC Number | General Stability | Organism |
|---|---|---|
| 3.1.4.54 | phenylmethylsulfonylfluoride stabilizes at high concentrations (10 mM) | Rattus norvegicus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.4.54 | methyl arachidonyl fluorophosphonate | above 0.1 mM | Rattus norvegicus |  |
| 3.1.4.54 | oleate | - |
Rattus norvegicus | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.1.4.54 | microsome | - |
Rattus norvegicus | - |
- |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.4.54 | N-acylphosphatidylethanolamine + H2O | Rattus norvegicus | - |
N-acylethanolamine + phosphatidate | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.4.54 | Rattus norvegicus | Q769K2 | - |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.4.54 | brain | - |
Rattus norvegicus | - |
| 3.1.4.54 | heart | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.4.54 | additional information | NAPE-PLD is not capable of catalysing a transphosphatidylation reaction | Rattus norvegicus | ? | - |
? | |
| 3.1.4.54 | N-acylphosphatidylethanolamine + H2O | - |
Rattus norvegicus | N-acylethanolamine + phosphatidate | - |
? | |
| 3.1.4.54 | N-palmitoyl-1-palmitoyl-2-oleoylphosphatidylethanolamine + H2O | - |
Rattus norvegicus | N-palmitoylethanolamine + 1-palmitoyl-2-oleoyl-sn-glycerol 3-phosphate | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.1.4.54 | NAPE-PLD | - |
Rattus norvegicus |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.1.4.54 | 37 | - |
assay at | Rattus norvegicus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.1.4.54 | 8 | - |
assay at | Rattus norvegicus |
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Release 2023.1 (January 2023)
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