Literature summary extracted from

Roumenina, L.T.; Jablonski, M.; Hue, C.; Blouin, J.; Dimitrov, J.D.; Dragon-Durey, M.A.; Cayla, M.; Fridman, W.H.; Macher, M.A.; Ribes, D.; Moulonguet, L.; Rostaing, L.; Satchell, S.C.; Mathieson, P.W.; Sautes-Fridman, C.; Loirat, C.; Regnier, C.H.; Halbwachs-Mecarelli, L.; Fremeaux-Bacchi, V.
Hyperfunctional C3 convertase leads to complement deposition on endothelial cells and contributes to atypical hemolytic uremic syndrome (2009), Blood, 114, 2837-2845.

General Stability

EC Number	General Stability	Organism
3.4.21.43	the C3 convertase is stabilized by the binding of properdin	Ovis aries
3.4.21.47	the C3 convertase is stabilized by the binding of properdin	Rattus norvegicus

EC Number	Organism	UniProt	Comment	Textmining
3.4.21.43	Ovis aries	-	-	-
3.4.21.47	Rattus norvegicus	-	-	-

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.21.43	erythrocyte	-	Ovis aries	-
3.4.21.47	serum	-	Rattus norvegicus	-

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.4.21.43	complement component C3 + H2O	-	Ovis aries	complement component C3a + complement component C3b	-	?
3.4.21.47	complement component C3 + H2O	-	Rattus norvegicus	complement component C3a + complement component C3b	-	?

EC Number	Synonyms	Comment	Organism
3.4.21.43	C3bBb	-	Ovis aries
3.4.21.43	classical pathway C3 convertase	-	Ovis aries
3.4.21.47	alternative pathway C3 convertase	-	Rattus norvegicus
3.4.21.47	C3bBb	-	Rattus norvegicus

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Release 2023.1 (January 2023)