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Literature summary extracted from

  • Choi, M.S.; Cho, K.S.; Shin, S.M.; Ko, H.M.; Kwon, K.J.; Shin, C.Y.; Ko, K.H.
    ATP induced microglial cell migration through non-transcriptional activation of matrix metalloproteinase-9 (2010), Arch. Pharm. Res., 33, 257-265.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.24.35 additional information ATP non-transcriptionally increases MMP-9 activity by activation of P2Y and PI3K, the increased activity of secreted MMP-9 is due to the increased protein secretion, but not by the increased MMP-9 mRNA and protein expression Mus musculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.35 GM6001 MMP-9-specific inhibitor Mus musculus
3.4.24.35 SB-3CT MMP-9-specific inhibitor Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.35 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.35 BV-2 cell
-
 Mus musculus
-
3.4.24.35 microglial cell
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.35 Gelatin + H2O
-
 Mus musculus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.35 Matrix metalloproteinase 9
-
 Mus musculus
3.4.24.35 MMP-9
-
 Mus musculus
3.4.24.35 Type IV collagen metalloproteinase
-
 Mus musculus