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Literature summary extracted from

  • Aberg, A.M.; Ronquist, G.; Haney, M.; Waldenstrom, A.
    Effects of some modulators on purine nucleoside phosphorylase activity in myocardial tissue (2010), Scand. J. Clin. Lab. Invest., 70, 8-14.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.2.1 EDTA
-
 Sus scrofa
2.4.2.1 staurosporine stimulation Sus scrofa
2.4.2.1 thapsigargin stimulation Sus scrofa

Application

EC Number Application Comment Organism
2.4.2.1 analysis determination of enzymic activity using commercially available substrate 2-amino-6-mercapto-7-methylpurine ribonucleoside and photometric assessment of the reaction Sus scrofa

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.2.1 adenosine 1 mM, about 20% inhibition Sus scrofa
2.4.2.1 EGTA
-
 Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.1 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.2.1 heart similar activity for ischemic tissue and normal tissue of hte same heart Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.1 2-amino-6-mercapto-7-methylpurine ribonucleoside + phosphate
-
 Sus scrofa alpha-D-ribose 1-phosphate + 2-amino-6-mercapto-7-methylpurine
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.2.1 37
-
-
 Sus scrofa

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.4.2.1 6 6.8
-
 Sus scrofa