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Literature summary extracted from

  • Baris, I.; Tuncel, A.; Ozber, N.; Keskin, O.; Kavakli, I.H.
    Investigation of the interaction between the large and small subunits of potato ADP-glucose pyrophosphorylase (2009), PLoS Comput. Biol., 5, e1000546.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.7.27 3-Phosphoglyceric acid
-
 Solanum tuberosum

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.7.27 the cDNAs of potato AGPase LS and SS are PCR amplified using pML7 and pML10 plasmids as template, respectively, and ligated into pGADT7 and pGBKT7 vectors for the yeast two-hybrid assay Solanum tuberosum

Protein Variants

EC Number Protein Variants Comment Organism
2.7.7.27 LSH342A large subunit mutant, substitution of a critical amino acid regarding the formation of the native heterotetrameric enzyme Solanum tuberosum
2.7.7.27 LSH89A large subunit mutant, substitution of a critical amino acid regarding the formation of the native heterotetrameric enzyme Solanum tuberosum
2.7.7.27 LSI330K large subunit mutant, substitution of a critical amino acid regarding the formation of the native heterotetrameric enzyme Solanum tuberosum
2.7.7.27 LSI335R large subunit mutant, substitution of a critical amino acid regarding the formation of the native heterotetrameric enzyme Solanum tuberosum
2.7.7.27 LSI339A/I330A large subunit mutant, substitution of critical amino acids regarding the formation of the native heterotetrameric enzyme Solanum tuberosum
2.7.7.27 LSK334A large subunit mutant, substitution of a critical amino acid regarding the formation of the native heterotetrameric enzyme Solanum tuberosum
2.7.7.27 LSK336A large subunit mutant, substitution of a critical amino acid regarding the formation of the native heterotetrameric enzyme Solanum tuberosum
2.7.7.27 LSN102A large subunit mutant, substitution of a critical amino acid regarding the formation of the native heterotetrameric enzyme Solanum tuberosum
2.7.7.27 LSN87A large subunit mutant, substitution of a critical amino acid regarding the formation of the native heterotetrameric enzyme Solanum tuberosum
2.7.7.27 LSP327A large subunit mutant, substitution of a critical amino acid regarding the formation of the native heterotetrameric enzyme Solanum tuberosum
2.7.7.27 LSR45A large subunit mutant, substitution of a critical amino acid regarding the formation of the native heterotetrameric enzyme Solanum tuberosum
2.7.7.27 LSR88A large subunit mutant, substitution of a critical amino acid regarding the formation of the native heterotetrameric enzyme Solanum tuberosum
2.7.7.27 LSR92A large subunit mutant, substitution of a critical amino acid regarding the formation of the native heterotetrameric enzyme Solanum tuberosum
2.7.7.27 LST328A/I330A large subunit mutant, substitution of critical amino acids regarding the formation of the native heterotetrameric enzyme Solanum tuberosum
2.7.7.27 LSW135A large subunit mutant, substitution of a critical amino acid regarding the formation of the native heterotetrameric enzyme Solanum tuberosum
2.7.7.27 LSW135R large subunit mutant, substitution of a critical amino acid regarding the formation of the native heterotetrameric enzyme Solanum tuberosum

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.7.27 inorganic phosphate
-
 Solanum tuberosum

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.7.27 Mg2+
-
 Solanum tuberosum

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.7.27 207000
-
 heterotetramer, determined by SDS-PAGE and Western blot analysis Solanum tuberosum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.27 ATP + alpha-D-glucose 1-phosphate Solanum tuberosum
-
 diphosphate + ADP-glucose
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.27 Solanum tuberosum
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.7.27 tuber
-
 Solanum tuberosum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.27 ATP + alpha-D-glucose 1-phosphate
-
 Solanum tuberosum diphosphate + ADP-glucose
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.7.27 heterotetramer the enzyme is composed of pairs of large, LS, and small subunits, SS Solanum tuberosum

Synonyms

EC Number Synonyms Comment Organism
2.7.7.27 ADP-glucose pyrophosphorylase
-
 Solanum tuberosum
2.7.7.27 AGPase
-
 Solanum tuberosum

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.7.27 ATP
-
 Solanum tuberosum

General Information

EC Number General Information Comment Organism
2.7.7.27 physiological function ADP-glucose pyrophosphorylase is a key allosteric enzyme involved in higher plants starch biosynthesis Solanum tuberosum