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Literature summary extracted from

  • Liu, M.; Eguchi, N.; Yamasaki, Y.; Urade, Y.; Hattori, N.; Urabe, T.
    Protective role of hematopoietic prostaglandin D synthase in transient focal cerebral ischemia in mice (2009), Neuroscience, 163, 296-307.
    View publication on PubMed

Application

EC Number Application Comment Organism
5.3.99.2 medicine the results demonstrate that the neuroprotective effects of hematopoietic prostaglandin D synthase in the model are mediated by suppression of activation and infiltration of inflammatory cells Mus musculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.3.99.2 4-benzhydryloxy-1-[3-(1H-tetrazol-5-yl)-propyl]piperidine HQL-79 Mus musculus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
5.3.99.2 26000
-
 determined by SDS-PAGE and Western Blot analysis Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.3.99.2 Prostaglandin H2 Mus musculus
-
 Prostaglandin D2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.3.99.2 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.3.99.2 brain ischemic region, contralateral cortex Mus musculus
-
5.3.99.2 microglia
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.3.99.2 Prostaglandin H2
-
 Mus musculus Prostaglandin D2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.3.99.2 Hematopoietic prostaglandin D synthase
-
 Mus musculus
5.3.99.2 HPGDS
-
 Mus musculus